Lupus Nephritis: Varying Complement-fixing Properties of Immunoglobulin G Antibodies to Antigens of Cell Nuclei

Overview

Journal Science

Specialty Science

Date 1968 Aug 30

PMID 4174454

Citations 25

Authors

T Tojo

G J Friou

Affiliations

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Abstract

Relative complement-fixing activity of antibodies to nuclear antigens, including DNA, were determined in serums of 15 patients with, and 65 patients without, active lupus nephritis, by comparing titers obtained in two methods. High complement-fixing activity of antibody was found in the nephritis group and low activity in the others. Results with immunoglobulin G fractions were similar.

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