Comparison of Superoxide with Other Reducing Agents in the Biological Production of Hydroxyl Radicals

Overview

Journal Biochem J

Specialty Biochemistry

Date 1979 Aug 15

PMID 41521

Citations 36

Authors

C C Winterbourn

Affiliations

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Abstract

Iron--EDTA was shown to catalyse OH. production from H2O2 and ascorbate by a mechanism largely independent of superoxide. When ascorbate and superoxide were both present, the ascorbate mechanism was more important than superoxide as a source of OH., and would appear to be more significantly biologically.

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