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Serotypes of Trachoma Agent Isolated in the Gambia: with an Observation on the Relation Between Serotype and Morphology

Overview
Journal J Hyg (Lond)
Specialty Public Health
Date 1974 Jun 1
PMID 4135585
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Abstract

Of 60 TRIC agents isolated from Gambian children with trachoma, 25 were serotype 1 and the remainder type 2. There was a pronounced difference in the proportions of these types in the two villages studied. In the village with a predominance of type 2 strains, TRIC agents remained confined to 2 adjacent compounds over a 14 month observation period. All 19 type 1 strains examined were characterized by the appearance in yolk sac smears of compact aggregates of elementary bodies; such aggregates were seen in only 2 of 35 type 2 strains, and may reflect a chemical difference in the surface of the elementary bodies or in a substance elaborated during their replication.

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