[Immunology of Histoplasmosis: Isolation of a Polysaccharide-protein Complex with Immuno-specific Activity from Histoplasma Capsulatum]

Overview

Journal Arch Invest Med (Mex)

Specialty General Medicine

Date 1977 Jan 1

PMID 410378

Citations 5

Authors

M L Taylor

L F BOJALIL

Affiliations

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Abstract

A polysaccharide protein complex (PPC) with a high specificity in immunodiffusion in gel (IDG) was isolated from a Histoplasma capsulatum strain. Although unaffected by proteolytic enzymes (pronase) and heat, the PPC antigen activity was destroyed by beta-glucosidase. These results suggest that the specificity of the PPC antigen might be located in the polysaccharide fraction. Polyacrylamide gel electrophoresis of the PPC antigen gave only one brand detected by Schiff's reagent (PAS).

Citing Articles

Two-dimensional immunoelectrophoresis of histoplasmin and a purified polysaccharide-protein antigen of Histoplasma capsulatum.

Toriello C, Reyes-Montes M, Taylor M Mycopathologia. 1993; 122(1):7-13.

PMID: 8326996 DOI: 10.1007/BF01103703.

Immunology of histoplasmosis: humoral and cellular activity from a polysaccharide-protein complex and its deproteinized fraction in experimentally immunized mice.

Taylor M, Reyes Montes M, Lachica A, Eslava Campos C, Olvera J, Maxwell R Mycopathologia. 1980; 71(3):159-66.

PMID: 7412854 DOI: 10.1007/BF00473064.

Antigens from Histoplasma capsulatum and Blastomyces dermatitidis. I. Immunological comparative studies from polysaccharide-protein complexes of both fungi.

Reyes-Montes M, Martinez A, Toriello C, Taylor M Mycopathologia. 1982; 78(1):17-23.

PMID: 6178974 DOI: 10.1007/BF00436577.

Immunomodulation by Histoplasma capsulatum products; polyclonal activation and mitogenic effects.

Ruiz B, Carvajal R Mycopathologia. 1986; 93(2):113-9.

PMID: 3487035 DOI: 10.1007/BF00437743.

Modifications of the immune response induced by Histoplasma capsulatum products.

Ruiz B, Carvajal R, Ortiz-Ortiz L Mycopathologia. 1990; 109(1):1-9.

PMID: 2183061 DOI: 10.1007/BF00436999.