The Raccoon Ascarid. A Probable Cause of Human Ocular Larva Migrans

Overview

Journal Ophthalmology

Publisher Elsevier

Specialty Ophthalmology

Date 1985 Dec 1

PMID 4088627

Citations 18

Authors

K R Kazacos

L A Raymond

E A Kazacos

W A Vestre

Affiliations

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Abstract

The ability of raccoon roundworm larvae, Baylisascaris procyonis, to produce ocular larva migrans (OLM) was studied in various experimental animals. In addition, the clinical and pathologic lesions were compared to those in suspected cases of human ocular baylisascariasis, in patients with diffuse unilateral subacute neuroretinitis (DUSN). Ocular larva migrans was produced in squirrel monkeys, cynomolgus monkeys, mice, hamsters, grey squirrels, and woodchucks orally infected with B. procyonis eggs. The clinical and histologic lesions were primarily those of retinitis, retinal hemorrhages, retinal tracks, disruption, and vasculitis; pigment migration; choroiditis; vitritis; and free or encysted larvae in ocular and extraocular tissues. The lesions of experimental OLM correlated well with those of suspected cases of human ocular baylisascariasis and DUSN. Based on these studies, B. procyonis of raccoons should be considered as a probable cause of OLM and DUSN in humans.

Citing Articles

Is it canine DUSN?: Another view of retinopathies, some acquired, and others possibly "inherited": Another view of retinopathies, some acquired, and others possibly "inherited".

Aguirre G, Kazacos K Vet Ophthalmol. 2021; 25(2):96-108.

PMID: 34894198 PMC: 10566749. DOI: 10.1111/vop.12951.

Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report.

Amaral C, Jimenez H, Davila P, Ulloa-Padilla J, Guiot H, Oliver A Am J Ophthalmol Case Rep. 2021; 22:101054.

PMID: 33748536 PMC: 7970060. DOI: 10.1016/j.ajoc.2021.101054.

Multimodal imaging-guided diagnosis, management and follow-up of a case of diffuse unilateral subacute neuroretinitis.

Ramachandran O, Mallidi R, Sen S, Kannan N BMJ Case Rep. 2020; 13(4).

PMID: 32300038 PMC: 7199107. DOI: 10.1136/bcr-2020-234737.

Diffuse unilateral subacute neuroretinitis: review article.

Mazzeo T, Motta M, Curi A J Ophthalmic Inflamm Infect. 2019; 9(1):23.

PMID: 31883049 PMC: 6934636. DOI: 10.1186/s12348-019-0191-x.

Case report: a case of diffuse unilateral subacute neuroretinitis (DUSN) in a child.

Curragh D, Ramsey A, Christie S, McLoone E BMC Ophthalmol. 2018; 18(Suppl 1):218.

PMID: 30255794 PMC: 6157124. DOI: 10.1186/s12886-018-0854-7.