Alpha 2.0
Login Register
» Articles » PMID: 4088290

In Vivo and in Vitro Characteristics of Six Paracoccidioides Brasiliensis Strains

Overview
Journal Mycopathologia
Specialties Microbiology
Pharmacology
Date 1985 Dec 1
PMID 4088290
Citations 31
Authors
S S Kashino
V L Calich
E Burger
Affiliations
Soon will be listed here.
Abstract

The yeast-like forms of six P. brasiliensis strains were characterized and compared using in vitro (growth curve determination) and in vivo (pathogenicity to sensitive inbred mice) criteria. Strains Pb 18 and Pb 265 which behaved similarly in vitro, showing low counts of fungi and long mean generation times, were respectively the most and the least pathogenic strains. Strains Pb 2052 and IVIC Pb 267, which grow abundantly in vitro were, respectively virulent and avirulent. Strains Pb SN and IVIC Pb 9 behaved similarly both in vitro and in vivo displaying an intermediate pattern of virulence and growing conditions.

Citing Articles

An improved high-performance liquid chromatography (HPLC) method for detection of variations in the hydroxyproline content of tissue homogenates from -infected mice.

Gidlund M, Molina R, Burger E J Venom Anim Toxins Incl Trop Dis. 2024; 30:e20230068.

PMID: 39055048 PMC: 11270750. DOI: 10.1590/1678-9199-JVATITD-2023-0068.

On the relationship between Pathogenic Potential and Infective Inoculum.

Smith D, Casadevall A PLoS Pathog. 2022; 18(6):e1010484.

PMID: 35696437 PMC: 9232127. DOI: 10.1371/journal.ppat.1010484.

Invariant Natural Killer T Cells as Key Players in Host Resistance against .

Nogueira-Neto J, Loures F, Schanoski A, Andrade D, Gonzatti M, Costa T J Immunol Res. 2021; 2021:6673722.

PMID: 33954206 PMC: 8064773. DOI: 10.1155/2021/6673722.

Eighty Years of Mycopathologia: A Retrospective Analysis of Progress Made in Understanding Human and Animal Fungal Pathogens.

Chaturvedi V, Bouchara J, Hagen F, Alastruey-Izquierdo A, Badali H, Bocca A Mycopathologia. 2018; 183(6):859-877.

PMID: 30506286 DOI: 10.1007/s11046-018-0306-1.

Effect of ArtinM on Human Blood Cells During Infection With .

Ruas L, Genaro L, Justo-Junior A, Coser L, de Castro L, Trabasso P Front Microbiol. 2018; 9:867.

PMID: 29780375 PMC: 5945982. DOI: 10.3389/fmicb.2018.00867.

References
1.
San-Blas G, Vernet D . Induction of the synthesis of cell wall alpha-1,3-glucan in the yeastlike form of Paracoccidioides brasiliensis strain IVIC Pb9 by fetal calf serum. Infect Immun. 1977; 15(3):897-902. PMC: 421458. DOI: 10.1128/iai.15.3.897-902.1977. View
2.
Calich V, Siqueira A, Burger E . Susceptibility and resistance of inbred mice to Paracoccidioides brasiliensis. Br J Exp Pathol. 1985; 66(5):585-94. PMC: 2042050. View
3.
. Growth curves and nucleic acids content of mycelial and yeast-like forms of Paracoccidioides brasiliensis. Mycopathol Mycol Appl. 1970; 41(3):203-10. DOI: 10.1007/BF02051098. View
4.
Restrepo A, Jimenez B . Growth of Paracoccidioides brasiliensis yeast phase in a chemically defined culture medium. J Clin Microbiol. 1980; 12(2):279-81. PMC: 273566. DOI: 10.1128/jcm.12.2.279-281.1980. View
5.
Linares L, Friedman L . Experimental paracoccidioidomycosis in mice. Infect Immun. 1972; 5(5):681-7. PMC: 422425. DOI: 10.1128/iai.5.5.681-687.1972. View