An Increase in Startle Response in Rats Administered Oxytocin

Overview

Journal Peptides

Specialty Biochemistry

Date 1985 May 1

PMID 4070019

Citations 5

Authors

M G King

R Brown

A Kusnecov

Affiliations

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Abstract

Twenty-four male albino Wistar rats were allocated to four groups and given either 23.2, 11.6 or 5.8 IU OXT/kg or vehicle (0.9% saline). A significant increase in startle response was observed in the 11.6 and 5.8 IU OXT/kg groups when compared to vehicle. Our results further support the suggestion that OXT is a "stress hormone" by implicating this peptide with increased emotionality/reactivity during a stressful experience.

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