Scintigraphic Demonstration of a Diaphragmatic Defect As the Cause of Massive Hydrothorax in Cirrhosis

Overview

Journal Eur J Nucl Med

Specialty Nuclear Medicine

Date 1985 Jan 1

PMID 4043113

Citations 2

Authors

A Serena

L Aliaga

J A Richter

R Calderon

L Sanchez

M A Charvet

Affiliations

Soon will be listed here.

Abstract

A 64-year-old man presented with a massive right-sided hydrothorax associated with cirrhosis of the liver. There was no clinical evidence of ascites nor other underlying disease. The usual complementary tests failed to demonstrate any causative abnormality. Chest and abdominal scintigraphy after intraperitoneal injection of 99mTc-human serum albumin disclosed early filling of the pleural space by the radiopharmaceutical and suggested a diaphragmatic defect as the cause for this rare association.

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References

EMERSON P, Davies J . Hydrothorax complicating ascites. Lancet. 1955; 268(6862):487-8. DOI: 10.1016/s0140-6736(55)90269-5. View

Coates G, Bush R, ASPIN N . A study of ascites using lymphoscintigraphy with 99m Tc-sulfur colloid. Radiology. 1973; 107(3):577-83. DOI: 10.1148/107.3.577. View

FARRER P, Friede J, Wexler M . Scintiphotographic evaluation of LeVeen peritoneo-venous shunt patency using intraperitoneal Tc-99m-MAA. Clin Nucl Med. 1979; 4(11):451-4. DOI: 10.1097/00003072-197911000-00002. View

Singer J, KAPLAN M, Katz R . Cirrhotic pleural effusion in the absence of ascites. Gastroenterology. 1977; 73(3):575-7. View

LUTTWAK E, Fabian R, Mordochovich D . Role of peritoneal absorption in ascites. Surg Gynecol Obstet. 1975; 141(5):693-8. View

Henriksen J, Lassen N, Parving H, Winkler K . Filtration as the main transport mechanism of protein exchange between plasma and the peritoneal cavity in hepatic cirrhosis. Scand J Clin Lab Invest. 1980; 40(6):503-13. DOI: 10.3109/00365518009091957. View

WILLIAMS Jr M . Pleural effusion produced by abdomino-pleural communication in a patient with Laennec's cirrhosis of the liver and ascites. Ann Intern Med. 1950; 33(1):216-21. DOI: 10.7326/0003-4819-33-1-216. View

Madeddu G, dOvidio N, Casu A, Mura R, Costanza C, Lai N . Evaluation of peritoneovenous shunt patency with Tc-99m labeled microspheres. J Nucl Med. 1983; 24(4):302-7. View

Kaplan W, Bloomer W, Jones A, Federschneider J, Knapp R . Mediastinal lymphoscintigraphy in ovarian cancer using intraperitoneal autologous technetium-99m-labelled erythrocytes. Br J Radiol. 1981; 54(638):126-31. DOI: 10.1259/0007-1285-54-638-126. View

10.

Lieberman F, HIDEMURA R, Peters R, Reynolds T . Pathogenesis and treatment of hydrothorax complicating cirrhosis with ascites. Ann Intern Med. 1966; 64(2):341-51. DOI: 10.7326/0003-4819-64-2-341. View

11.

Lieberman F, Peters R . Cirrhotic hydrothorax. Further evidence that an acquired diaphragmatic defect is at fault. Arch Intern Med. 1970; 125(1):114-7. DOI: 10.1001/archinte.125.1.114. View

12.

CROFTS N . Pneumothorax complicating therapeutic pneumoperitoneum. Thorax. 1954; 9(3):226-8. PMC: 1019389. DOI: 10.1136/thx.9.3.226. View

13.

McKAY D, SPARLING Jr H, Robbins S . Cirrhosis of the liver with massive hydrothorax. Arch Intern Med (Chic). 2010; 79(5):501-9. DOI: 10.1001/archinte.1947.00220110041002. View

14.

Johnston R, LOO R . HEPATIC HYDROTHORAX; STUDIES TO DETERMINE THE SOURCE OF THE FLUID AND REPORT OF THIRTEEN CASES. Ann Intern Med. 1964; 61:385-401. DOI: 10.7326/0003-4819-61-3-385. View

15.

Morrow C, Kantor M, ARMEN R . Hepatic hydrothorax. Ann Intern Med. 1958; 49(1):193-203. DOI: 10.7326/0003-4819-49-1-193. View