IgA Anti-endomysial Antibody Detection in the Serum of Patients with Dermatitis Herpetiformis Following Gluten Challenge

Overview

Journal Arch Dermatol Res

Specialty Dermatology

Date 1985 Jan 1

PMID 4026376

Citations 4

Authors

J N Leonard

T P Chorzelski

E H BEUTNER

J Sulej

C E Griffiths

V J Kumar

L Fry

Affiliations

Soon will be listed here.

Abstract

This study reports the appearance of IgA-class anti-endomysial antibodies in the serum of 8 out of 12 patients with dermatitis herpetiformis who were challenged with gluten after a number of years of control of the rash with a strict gluten-free diet. Although there was no evidence for the antibodies having any pathogenic role in the rash of dermatitis herpetiformis, their presence may be related to the deterioration in the gluten-sensitive enteropathy.

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Immunoglobulin A (IgA) deficiency and alternative celiac disease-associated antibodies in sera submitted to a reference laboratory for endomysial IgA testing.

PRINCE H, Norman G, Binder W Clin Diagn Lab Immunol. 2000; 7(2):192-6.

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Antiendomysial antibody--useful serological indicator of dermatitis herpetiformis.

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Comparison of IgA-class reticulin and endomysium antibodies in coeliac disease and dermatitis herpetiformis.

Hallstrom O Gut. 1989; 30(9):1225-32.

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