Succinic and Malic Dehydrogenase Histochemical Activities in Cerebral, Cerebellar and Neostriatum Sections Incubated in Presence of D-amphetamine

Overview

Journal Acta Neuropathol

Specialty Neurology

Date 1985 Jan 1

PMID 4024873

Citations 1

Authors

R Martinez-Murillo

R Martinez-Rodriguez

G Arenas

L Franic

A Hernandez

F Estrada

Affiliations

Soon will be listed here.

Abstract

The action of d-amphetamine on the histochemical activities of succinic and malic dehydrogenases in sections of cerebral cortex, cerebellum, and neostriatum has been studied. Meldola blue was used as an exogenous electron carrier in the histochemical reactions. The results have demonstrated that d-amphetamine increases the activity of the enzymes studied.

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PMID: 18351285 DOI: 10.1007/s00702-008-0040-9.

References

Nahorski S, Rogers K . The role of catecholamines in the action of amphetamine and L-DOPA on cerebral energy metabolism. Neuropharmacology. 1975; 14(4):283-90. DOI: 10.1016/0028-3908(75)90074-x. View

Walker D, Seligman A . Formalin fixation in the cytochemical demonstration of succinic dehydrogenase of mitochondria. J Biophys Biochem Cytol. 1961; 9:415-27. PMC: 2225007. DOI: 10.1083/jcb.9.2.415. View

Meijer A . Adaptations of methods in enzyme histochemistry to the different metabolic conditions in cells and tissues. Cell Mol Biol Incl Cyto Enzymol. 1978; 23(2):159-70. View

Heywood L, Blackshaw A . Lactate-dehydrogenase activity in the rat testis: a comparison between fluorometric assay of freeze-dried sections and histochemical localization with phenazine methosulphate. J Histochem Cytochem. 1978; 26(11):967-72. DOI: 10.1177/26.11.722053. View

Altman F . Tetrazolium salts and formazans. Prog Histochem Cytochem. 1976; 9(3):1-56. DOI: 10.1016/s0079-6336(76)80015-0. View

Creese I, Burt D, Snyder S . Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science. 1976; 192(4238):481-3. DOI: 10.1126/science.3854. View

Burd J, Usategui-Gomez M . A colorimetric assay for serum lactate dehydrogenase. Clin Chim Acta. 1973; 46(3):223-7. DOI: 10.1016/0009-8981(73)90174-5. View

BERCHTOLD J . Ultrastructural demonstration of glucose-6-phosphate dehydrogenase activity in steroid-secreting cells. Histochemistry. 1979; 63(2):173-80. DOI: 10.1007/BF00644539. View

Garbarsch C, Andersen H, Hoyer P . Succinate dehydrogenase activity in the wall of rabbit aorta. The histochemical use of PMS and exogenous coenzyme Q10 as intermediate carriers. Histochemistry. 1978; 57(4):297-304. DOI: 10.1007/BF00492665. View

10.

Nahorski S, Rogers K . In vivo effects of amphetamine on metabolites and metabolic rate in brain. J Neurochem. 1973; 21(3):679-86. DOI: 10.1111/j.1471-4159.1973.tb06012.x. View

11.

Kugler P, Wrobel K . Meldola blue: a new electron carrier for the histochemical demonstration of dehydrogenases (SDH, LDH, G-6-PDH). Histochemistry. 1978; 59(2):97-109. DOI: 10.1007/BF00518505. View

12.

Hagerdal M, Siesjo B . Influence of amphetaime sulphate on cerebral flood flow and metabolism. Acta Physiol Scand. 1975; 94(1):128-9. DOI: 10.1111/j.1748-1716.1975.tb05868.x. View

13.

Raap A, VAN DUIJN P . Studies on the phenazine methosulphate-tetrazolium capture reaction in NAD(P)+-dependent dehydrogenase cytochemistry. II. A novel hypothesis for the mode of action of PMS and a study of the properties of reduced PMS. Histochem J. 1983; 15(9):881-93. DOI: 10.1007/BF01011827. View

14.

Farber E, Bueding E . Histochemical localization of specific oxidative enzymes. V. The dissociation of succinic dehydrogenase from carriers by lipase and the specific histochemical localization of the dehydrogenase with phenazine methosulfate and tetrazolium salts. J Histochem Cytochem. 1956; 4(4):357-62. DOI: 10.1177/4.4.357. View

15.

Martinez-Rodriguez R, Martinez-Murillo R . In vitro d-amphetamine action on oxido-reductase activity of several rat nervous centres. Acta Histochem. 1984; 74(1):85-90. DOI: 10.1016/S0065-1281(84)80033-1. View

16.

McCulloch J, Harper A . Cerebral circulatory and metabolism changes following amphetamine administration. Brain Res. 1977; 121(1):196-9. DOI: 10.1016/0006-8993(77)90452-8. View