Revolutionary Cancer Therapy for Personalization and Improved Efficacy: Strategies to Overcome Resistance to Immune Checkpoint Inhibitor Therapy
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Abstract
Cancer remains a significant public health issue worldwide, standing as a primary contributor to global mortality, accounting for approximately 10 million fatalities in 2020 [...].
References
1.
Suzuki A, Itami S, Ohishi M, Hamada K, Inoue T, Komazawa N
. Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation. Cancer Res. 2003; 63(3):674-81.
View
2.
Xiao Y, Li Z, Zhong N, Cao L, Liu B, Bu L
. Charting new frontiers: Co-inhibitory immune checkpoint proteins in therapeutics, biomarkers, and drug delivery systems in cancer care. Transl Oncol. 2023; 38:101794.
PMC: 10582482.
DOI: 10.1016/j.tranon.2023.101794.
View
3.
Fukumura D, Kloepper J, Amoozgar Z, Duda D, Jain R
. Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges. Nat Rev Clin Oncol. 2018; 15(5):325-340.
PMC: 5921900.
DOI: 10.1038/nrclinonc.2018.29.
View
4.
Mariathasan S, Turley S, Nickles D, Castiglioni A, Yuen K, Wang Y
. TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells. Nature. 2018; 554(7693):544-548.
PMC: 6028240.
DOI: 10.1038/nature25501.
View
5.
Socinski M, Jotte R, Cappuzzo F, Orlandi F, Stroyakovskiy D, Nogami N
. Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC. N Engl J Med. 2018; 378(24):2288-2301.
DOI: 10.1056/NEJMoa1716948.
View