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(3)-obscurolide A: a New Obscurolide from SA-7 Isolated from Soil of the North Western Himalayas

Overview
Journal Nat Prod Res
Specialty Biology
Date 2025 Mar 12
PMID 40071789
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Abstract

A new obscurolide, (3 )-obscurolide A () and four previously identified metabolites streptalbonin F (), chartreusin (), TAN 1364B () and streptalbonin G () were isolated from SA-7, obtained from soil of the North Western Himalayas. The structure of new compound (3 )-obscurolide A () was elucidated by spectroscopic data analysis, including 1D and 2D NMR, and HR-ESI-MS, while the known compounds (-) were identified by comparing their spectral data with the literature. Notably, chartreusin () is a well-known antimicrobial agent with broad-spectrum activity, while the other compounds had been reported to display moderate antimicrobial effects against various test strains.