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Correlation of Anthropometric Measurements with Insulin Resistance Assessed by HOMA-IR in Obese Normotensive Individuals: A Cross-Sectional Study in South India

Overview
Journal J Pharm Bioallied Sci
Specialty Pharmacology
Date 2025 Mar 10
PMID 40061765
Authors
S Swarupa Gnana Sudha Meriam
Karunya Varsha Ragavendran Susethira
B S Saravanan
Susethira Aruppukottai Rajendran
Panneerselvam Periasamy
Sasikala Gunasekaran
Affiliations
Soon will be listed here.
Abstract

Background: The study aims to evaluate insulin resistance in obese individuals with normotensive diabetes using Homeostasis Model Assessment and correlate it with anthropometric measurements, highlighting the link between poor lifestyles and metabolic syndrome.

Methods: The research assessed the anthropometric, lipid, fasting blood glucose, hemoglobin A1C, serum insulin, and lipidosis profiles of 100 people using both traditional procedures and the Homeostatic model assessment (HOMA)-IR.

Results: A study of 100 participants, including 43 males and 57 females, found a significant waist-hip ratio (HOMA-IR >2.5) among the group, indicating a high level of health.

Conclusions: The research discovered notable connections between anthropometric measurements and clinical and biochemical factors associated with insulin resistance, with subscapular skinfold thickness demonstrating more robust linkages.

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