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Steroid-induced Activated White Adipose Tissue on FDG PET-CT

Overview
Specialty Nuclear Medicine
Date 2025 Mar 10
PMID 40061506
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Abstract

White adipose tissue (WAT) generally has negligible glucose utilization and thus, shows no or insignificant Fluorine-18 fluoro D-glucose (FDG) uptake. However, corticosteroids can cause altered biodistribution of FDG with increased uptake in WAT. We hereby describe a case of immune complex-mediated glomerulonephritis showing diffusely increased FDG uptake in WAT secondary to high-dose corticosteroid therapy.

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