Parietal Cortex is Recruited by Frontal and Cingulate Areas to Support Action Monitoring and Updating During Stopping

Overview

Journal bioRxiv

Date 2025 Mar 10

PMID 40060422

Authors

Jung Uk Kang

Layth Mattar

Jose Vergara

Victoria E Gobo

Hernan G Rey

Sarah R Heilbronner

Andrew J Watrous

Benjamin Y Hayden

Sameer A Sheth

Eleonora Bartoli

Affiliations

Soon will be listed here.

Abstract

In Brief: Functional connectivity between the intraparietal sulcus (IPS) and a set of frontal and cingulate regions indicates that IPS is recruited to aid inhibitory control. Control failures are associated with increased communication with posterior cingulate. IPS could be a novel and tractable neuromodulation target for control-related neuropsychiatric disorders.

Highlights: Parietal cortex displays performance-dependent activity in action stoppingFunctional connectivity between IPS and IFG underlies successful stoppingEarly communication from ACC and OFC to IPS is also specific to successful stoppingCommunication from PCC to IPS is higher during lapses in control.

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