Fever Among Pertussis Cases Reported Through Enhanced Pertussis Surveillance, 2015-2022

Overview

Journal Open Forum Infect Dis

Specialty Infectious Diseases

Date 2025 Mar 10

PMID 40059981

Authors

Michelle M Hughes

Amy Rubis

Anna M Acosta

Vanessa Aden

Patricia Firmender

Kate Horn

Emma Stanislawski

Rachel Wester

Erin Youngkin

Victor Cruz

Tami H Skoff

Affiliations

Soon will be listed here.

Abstract

Fever is not considered a typical presentation of pertussis. We characterized fever among 7840 pertussis cases from the Centers for Disease Control and Prevention's Enhanced Pertussis Surveillance with cough onset from 2015 to 2022. Ten percent of cases had a reported fever. The presence of fever should not rule out pertussis as a cause of cough illness.

References

Liang J, Tiwari T, Moro P, Messonnier N, Reingold A, Sawyer M . Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2018; 67(2):1-44. PMC: 5919600. DOI: 10.15585/mmwr.rr6702a1. View

Barbosa F, Barnett E, Gautret P, Schlagenhauf P, van Genderen P, Grobusch M . Bordetella pertussis infections in travelers: data from the GeoSentinel global network. J Travel Med. 2017; 24(3). DOI: 10.1093/jtm/taw094. View

Moore A, Ashdown H, Shinkins B, Roberts N, Grant C, Lasserson D . Clinical Characteristics of Pertussis-Associated Cough in Adults and Children: A Diagnostic Systematic Review and Meta-Analysis. Chest. 2017; 152(2):353-367. DOI: 10.1016/j.chest.2017.04.186. View

Skoff T, Baumbach J, Cieslak P . Tracking Pertussis and Evaluating Control Measures through Enhanced Pertussis Surveillance, Emerging Infections Program, United States. Emerg Infect Dis. 2015; 21(9):1568-73. PMC: 4550149. DOI: 10.3201/eid2109.150023. View

Warfel J, Beren J, Kelly V, Lee G, Merkel T . Nonhuman primate model of pertussis. Infect Immun. 2012; 80(4):1530-6. PMC: 3318410. DOI: 10.1128/IAI.06310-11. View

Vittucci A, Spuri Vennarucci V, Grandin A, Russo C, Lancella L, Tozzi A . Pertussis in infants: an underestimated disease. BMC Infect Dis. 2016; 16(1):414. PMC: 4986228. DOI: 10.1186/s12879-016-1710-0. View

McNamara L, Skoff T, Faulkner A, Miller L, Kudish K, Kenyon C . Reduced Severity of Pertussis in Persons With Age-Appropriate Pertussis Vaccination-United States, 2010-2012. Clin Infect Dis. 2017; 65(5):811-818. PMC: 5755965. DOI: 10.1093/cid/cix421. View

Havers F, Moro P, Hunter P, Hariri S, Bernstein H . Use of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccines: Updated Recommendations of the Advisory Committee on Immunization Practices - United States, 2019. MMWR Morb Mortal Wkly Rep. 2020; 69(3):77-83. PMC: 7367039. DOI: 10.15585/mmwr.mm6903a5. View

Chen C, Balderston McGuiness C, Krishnarajah G, Blanchette C, Wang Y, Sun K . Estimated incidence of pertussis in people aged <50 years in the United States. Hum Vaccin Immunother. 2016; 12(10):2536-2545. PMC: 5085009. DOI: 10.1080/21645515.2016.1186313. View

10.

Bouchez V, Guiso N . Bordetella pertussis, B. parapertussis, vaccines and cycles of whooping cough. Pathog Dis. 2015; 73(7). DOI: 10.1093/femspd/ftv055. View

11.

Gentile A, Romanin V, Juarez M, Lucion M, Marques M, Mistchenko A . Epidemiology of Bordetella pertussis in a children's hospital. Arch Argent Pediatr. 2014; 112(1):26-32. DOI: 10.5546/aap.2014.eng.26. View

12.

Hughes M, Englund J, Kuypers J, Tielsch J, Khatry S, Shrestha L . Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal. J Pediatric Infect Dis Soc. 2017; 6(1):33-39. PMC: 5907881. DOI: 10.1093/jpids/piw079. View