» Articles » PMID: 40044898

Restoring Vision with Optogenetics

Overview
Journal Nature
Specialty Science
Date 2025 Mar 5
PMID 40044898
Authors
Affiliations
Soon will be listed here.
References
1.
Nagel G, Szellas T, Huhn W, Kateriya S, Adeishvili N, Berthold P . Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc Natl Acad Sci U S A. 2003; 100(24):13940-5. PMC: 283525. DOI: 10.1073/pnas.1936192100. View

2.
Bi A, Cui J, Ma Y, Olshevskaya E, Pu M, Dizhoor A . Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron. 2006; 50(1):23-33. PMC: 1459045. DOI: 10.1016/j.neuron.2006.02.026. View

3.
Lagali P, Balya D, Awatramani G, Munch T, Kim D, Busskamp V . Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nat Neurosci. 2008; 11(6):667-75. DOI: 10.1038/nn.2117. View

4.
Busskamp V, Duebel J, Balya D, Fradot M, Viney T, Siegert S . Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa. Science. 2010; 329(5990):413-7. DOI: 10.1126/science.1190897. View

5.
Sahel J, Boulanger-Scemama E, Pagot C, Arleo A, Galluppi F, Martel J . Partial recovery of visual function in a blind patient after optogenetic therapy. Nat Med. 2021; 27(7):1223-1229. DOI: 10.1038/s41591-021-01351-4. View