» Articles » PMID: 40034963

A Case of Infraorbital B-cell Lymphoma Masquerading As an Abscess

Overview
Specialty Oncology
Date 2025 Mar 4
PMID 40034963
Authors
Affiliations
Soon will be listed here.
Abstract

Background/aim: Primary ocular adnexal lymphomas pose a diagnostic challenge for physicians due to their nonspecific symptom presentation and resemblance to other periorbital masses, such as skin and soft tissue infections. Early diagnosis and appropriate management are crucial for optimizing outcomes and coordination of therapy.

Case Report: We present a case of a 67-year-old male with a history of infraorbital trauma, initially managed as a soft tissue infection, which was later revealed to be a large B-cell lymphoma. Despite multiple specialty evaluations, including dermatology, ophthalmology, plastic surgery, and ENT, among others, diagnosis was delayed, leading to worsening symptoms and vision impairment.

Conclusion: This case highlights the importance of considering ocular adnexal lymphomas in the differential diagnosis of periorbital masses and the need for interdisciplinary collaboration for timely recognition and treatment.

References
1.
Kirkegaard M . Ocular adnexal lymphoma: Subtype-specific clinical and genetic features. Acta Ophthalmol. 2022; 100 Suppl 270:3-37. DOI: 10.1111/aos.15248. View

2.
Chaurasiya B, Agrawal G, Chaudhary S, Shah S, Pradhan A, Lavaju P . Orbital Lymphoma Masquerading as Orbital Cellulitis. Case Rep Ophthalmol Med. 2021; 2021:8832783. PMC: 8445722. DOI: 10.1155/2021/8832783. View

3.
Moslehi R, Schymura M, Nayak S, Coles F . Ocular adnexal non-Hodgkin's lymphoma: a review of epidemiology and risk factors. Expert Rev Ophthalmol. 2013; 6(2):181-193. PMC: 3749740. DOI: 10.1586/eop.11.15. View

4.
Ferreri A, Govi S, Pasini E, Mappa S, Bertoni F, Zaja F . Chlamydophila psittaci eradication with doxycycline as first-line targeted therapy for ocular adnexae lymphoma: final results of an international phase II trial. J Clin Oncol. 2012; 30(24):2988-94. DOI: 10.1200/JCO.2011.41.4466. View

5.
Jeon Y, Yang H, Choi B, Jung S, Park K, O J . Comparison of Selection and Long-term Clinical Outcomes Between Chemotherapy and Radiotherapy as Primary Therapeutic Modality for Ocular Adnexal MALT Lymphoma. EClinicalMedicine. 2019; 4-5:32-42. PMC: 6537565. DOI: 10.1016/j.eclinm.2018.10.001. View