131I-meta-iodobenzylguanidine Scintigraphy of Neuroblastomas
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Sixteen neuroblastoma patients have been studied by 131I-meta-iodobenzylguanidine (MIBG) scintigraphy. Three patients were possibly cured, and their scintigraphy results were normal. Thirteen patients had tumors and metastases demonstrated by 131I-MIBG, two of these patients had a normal vanillylmandelic acid (VMA) excretion level. One patient has been treated by 131I-MIBG, but died. 131I-MIBG was concentrated in other cells too, eg, in erythrocytes and platelets.
Naranjo A, Parisi M, Shulkin B, London W, Matthay K, Kreissman S Pediatr Blood Cancer. 2011; 56(7):1041-5.
PMID: 21328522 PMC: 4581540. DOI: 10.1002/pbc.22991.
Nuclear medicine: metaiodobenzylguanidine in the diagnosis of pheochromocytoma and neuroblastoma.
Hattner R West J Med. 1988; 148(4):451.
PMID: 18750402 PMC: 1026138.
Neuroblastoma: evolving therapies for a disease with many faces.
Goldsby R, Matthay K Paediatr Drugs. 2004; 6(2):107-22.
PMID: 15035651 DOI: 10.2165/00148581-200406020-00004.
Lastoria S, Maurea S, Caraco C, Vergara E, Maurelli L, Indolfi P Eur J Nucl Med. 1993; 20(12):1161-7.
PMID: 8299651 DOI: 10.1007/BF00171014.
Montravers F, Coutris G, Sarda L, Mensch B, Talbot J Eur J Nucl Med. 1993; 20(11):1070-7.
PMID: 8287875 DOI: 10.1007/BF00173485.