Components and Biological Activities of Venom from Lionfishes (Scorpaenidae: )

Overview

Journal Mar Drugs

Publisher MDPI

Specialties Biology
Pharmacology

Date 2025 Feb 25

PMID 39997179

Authors

Candelario Rodriguez

Jafeth Carrasco

Gaspar Bruner-Montero

Osmindo Rodrigues Pires Junior

Marcelino Gutierrez

Edgardo Diaz-Ferguson

Affiliations

Soon will be listed here.

Abstract

Fishes of the genus possess spines that provoke intense pain, which can last for weeks. Since the first toxicological description of their spine venom, a significant amount of research has been published regarding their biochemical characterization. This minireview presents research published from 1959 to 2024 on bioactive substances found in species. venom mainly contains peptides and proteins that display a range of biological activities, including anticancer, antimicrobial, antioxidant, antiviral, enzymatic, cardiovascular, procoagulant, neurological, neuromuscular, and nutraceutical effects. Although venom contains bioactive substances, the toxic side effects, such as hemolysis and nociception, of these venoms should be considered. Hence, further intense research is needed to establish the potential uses of venom for human health.

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