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Rare Cause of Chronic Cough in a Young Healthcare Worker - A Case of Exogenous Lipoid Pneumonia!

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Specialty Public Health
Date 2025 Feb 24
PMID 39989543
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Abstract

Exogenous lipoid pneumonia (ELP) is a rarely reported entity caused by aspirating or inhaling fat or oil-containing substances. Clinically, patients present with subacute to chronic-onset non-specific symptoms such as cough, fever, breathlessness, and general malaise. In addition, lobar or multifocal interstitial and parenchymal infiltrates on chest imaging can mimic any other infectious etiology. Diagnosis of lipoid pneumonia is often missed or delayed in many cases and requires a high index of clinical suspicion. We report a case of a 36-year-old nursing officer who presented with a cough and right-sided pneumonia on chest imaging. She was being treated empirically with antitubercular therapy without any clinical response to the treatment. ELP was diagnosed after carefully evaluating the radiological findings, reviewing the clinical history, and finding supportive evidence of lipid-laden alveolar macrophages in her broncho-alveolar lavage fluid. It is vital to uphold a heightened clinical suspicion for non-infectious etiologies in non-resolving pneumonia and investigate the patient thoroughly before resorting to empirical treatments.

References
1.
Sias S, Daltro P, Marchiori E, Ferreira A, Caetano R, Silva C . Clinic and radiological improvement of lipoid pneumonia with multiple bronchoalveolar lavages. Pediatr Pulmonol. 2009; 44(4):309-15. DOI: 10.1002/ppul.20918. View

2.
Amato G, Novara V, Amato G . [Lipid pneumonia. Favorable outcome after treatment with intravenous immunoglobulins, steroids, cephalosporins]. Minerva Pediatr. 1997; 49(4):163-9. View

3.
Betancourt S, Martinez-Jimenez S, Rossi S, Truong M, Carrillo J, Erasmus J . Lipoid pneumonia: spectrum of clinical and radiologic manifestations. AJR Am J Roentgenol. 2009; 194(1):103-9. DOI: 10.2214/AJR.09.3040. View

4.
Marchiori E, Zanetti G, Mano C, Hochhegger B . Exogenous lipoid pneumonia. Clinical and radiological manifestations. Respir Med. 2010; 105(5):659-66. DOI: 10.1016/j.rmed.2010.12.001. View

5.
LAUGHLEN G . Studies on Pneumonia Following Naso-Pharyngeal Injections of Oil. Am J Pathol. 2009; 1(4):407-414.1. PMC: 1931653. View