The Effects of COVID-19 on Tinnitus Severity and Quality of Life in Individuals With Subjective Tinnitus

Overview

Journal Brain Behav

Specialty Psychology

Date 2025 Feb 20

PMID 39972979

Authors

Zehra Aydogan

Mehmet Can

Emre Soylemez

Kursad Karakoc

Zahide Ciler Buyukatalay

Suna Tokgoz Yilmaz

Affiliations

Soon will be listed here.

Abstract

Purpose: This study aimed to investigate the effects of the SARS-CoV-2 virus (COVID-19) on tinnitus severity and quality of life in infected and non-infected individuals who were re-admitted to our clinic after the COVID-19 outbreak.

Methods: The study involved both retrospective and prospective data analysis. The study included 30 individuals aged 20-65 years with normal hearing who had undergone psychoacoustic, tinnitus, and psychosomatic evaluations before the pandemic. Participants were divided into Group 1 (n = 15, COVID-19 negative) and Group 2 (n = 15, COVID-19 positive). Before the pandemic, tinnitus-related evaluations of all participants (i.e., pure tone audiometry [PTA], tinnitus frequency, loudness, minimum masking level [MML], and residual inhibition [RI]) were conducted, and the Tinnitus Handicap Inventory (THI), Visual Analog Scale (VAS), and Short Form 36 (SF-36) were administered to all participants. All assessments were repeated after the outbreak of the pandemic.

Results: There was no significant difference in the mean PTA thresholds of both groups before and after the pandemic (p > 0.05). There was a significant increase in tinnitus severity after COVID-19 infection in Group 2 (p < 0.05). Moreover, it was found that the VAS (loudness and annoyance), THI (functional, emotional, catastrophic, and total score), and SF-36 (physical function, physical role, pain, general health, vitality, emotional role, and social function) values worsened significantly compared to before COVID-19 infection (p < 0.05). In Group 1, the only significant differences were found in the THI emotional subdomain and the SF-36 emotional and general health subdomains (p < 0.05). No significant differences were found in the other evaluations of Group 1, neither before nor after the pandemic (p > 0.05).

Conclusion: Although negative effects of the pandemic were observed in individuals with tinnitus who were not infected with COVID-19, both the quality of life and tinnitus severity of individuals with tinnitus who were infected with COVID-19 worsened.

References

Almufarrij I, Munro K . One year on: an updated systematic review of SARS-CoV-2, COVID-19 and audio-vestibular symptoms. Int J Audiol. 2021; 60(12):935-945. DOI: 10.1080/14992027.2021.1896793. View

Aydogan Z, Cinar Satekin M, Ocak E, Tokgoz Yilmaz S . Effects of the coronavirus disease 2019 pandemic on subjective tinnitus perception. J Laryngol Otol. 2022; 136(5):410-413. PMC: 8961067. DOI: 10.1017/S0022215122000640. View

Fioretti A, Natalini E, Triggianese G, Eibenstein R, Angelone A, Lauriello M . Impact of the COVID-19 Lockdown on Patients with Chronic Tinnitus-Preliminary Results. Audiol Res. 2022; 12(3):327-336. PMC: 9220770. DOI: 10.3390/audiolres12030034. View

Kartal A, Kilic M . Tinnitus in patients recovering after COVID-19: observational and cross-sectional study. Eur Arch Otorhinolaryngol. 2022; 280(2):573-580. DOI: 10.1007/s00405-022-07501-9. View

Andersson G, McKenna L . The role of cognition in tinnitus. Acta Otolaryngol Suppl. 2006; (556):39-43. DOI: 10.1080/03655230600895226. View

Freni F, Meduri A, Gazia F, Nicastro V, Aragona P, Galletti C . Symptomatology in head and neck district in coronavirus disease (COVID-19): A possible neuroinvasive action of SARS-CoV-2. Am J Otolaryngol. 2020; 41(5):102612. PMC: 7301823. DOI: 10.1016/j.amjoto.2020.102612. View

Aydogan Z, Satekin M, Uyar M, Aksoy S, Tokgoz-Yilmaz S . Transcutaneous Electric Nerve Stimulation in Chronic Subjective Tinnitus. Am J Otolaryngol. 2022; 43(5):103521. DOI: 10.1016/j.amjoto.2022.103521. View

Henry J, Roberts L, Caspary D, Theodoroff S, Salvi R . Underlying mechanisms of tinnitus: review and clinical implications. J Am Acad Audiol. 2014; 25(1):5-22. PMC: 5063499. DOI: 10.3766/jaaa.25.1.2. View

Ozdin S, Bayrak Ozdin S . Levels and predictors of anxiety, depression and health anxiety during COVID-19 pandemic in Turkish society: The importance of gender. Int J Soc Psychiatry. 2020; 66(5):504-511. PMC: 7405629. DOI: 10.1177/0020764020927051. View

10.

Erinc M, Mutlu A, Celik S, Kalcioglu M, Szczepek A . Long-Term Effects of COVID-19 and the Pandemic on Tinnitus Patients. Front Neurol. 2022; 13:921173. PMC: 9279732. DOI: 10.3389/fneur.2022.921173. View

11.

Beukes E, Baguley D, Jacquemin L, Lourenco M, Allen P, Onozuka J . Changes in Tinnitus Experiences During the COVID-19 Pandemic. Front Public Health. 2020; 8:592878. PMC: 7676491. DOI: 10.3389/fpubh.2020.592878. View

12.

Makar S . Etiology and Pathophysiology of Tinnitus - A Systematic Review. Int Tinnitus J. 2021; 25(1):76-86. DOI: 10.5935/0946-5448.20210015. View

13.

Wilson P, Henry J, Bowen M, Haralambous G . Tinnitus reaction questionnaire: psychometric properties of a measure of distress associated with tinnitus. J Speech Hear Res. 1991; 34(1):197-201. View

14.

Janiri D, Carfi A, Kotzalidis G, Bernabei R, Landi F, Sani G . Posttraumatic Stress Disorder in Patients After Severe COVID-19 Infection. JAMA Psychiatry. 2021; 78(5):567-569. PMC: 7893542. DOI: 10.1001/jamapsychiatry.2021.0109. View

15.

Mazurek B, Haupt H, Olze H, Szczepek A . Stress and tinnitus-from bedside to bench and back. Front Syst Neurosci. 2012; 6:47. PMC: 3371598. DOI: 10.3389/fnsys.2012.00047. View

16.

Lough M, Almufarrij I, Whiston H, Munro K . Revised meta-analysis and pooled estimate of audio-vestibular symptoms associated with COVID-19. Int J Audiol. 2021; 61(8):705-709. DOI: 10.1080/14992027.2021.1962552. View

17.

Beukes E, Ulep A, Eubank T, Manchaiah V . The Impact of COVID-19 and the Pandemic on Tinnitus: A Systematic Review. J Clin Med. 2021; 10(13). PMC: 8268057. DOI: 10.3390/jcm10132763. View

18.

Eggermont J, Roberts L . The neuroscience of tinnitus. Trends Neurosci. 2004; 27(11):676-82. DOI: 10.1016/j.tins.2004.08.010. View

19.

Mui B, Leong N, Keil B, Domingo D, Dafny H, Manchaiah V . COVID-19 and tinnitus: an initiative to improve tinnitus care. Int J Audiol. 2022; 62(9):826-834. DOI: 10.1080/14992027.2022.2104175. View

20.

Viola P, Ralli M, Pisani D, Malanga D, Sculco D, Messina L . Tinnitus and equilibrium disorders in COVID-19 patients: preliminary results. Eur Arch Otorhinolaryngol. 2020; 278(10):3725-3730. PMC: 7582442. DOI: 10.1007/s00405-020-06440-7. View