Changes in the Glutathione Status of Plasma, Liver and Muscle Following Exhaustive Exercise in Rats

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 1985 Jun 17

PMID 3996604

Citations 40

Authors

H Lew

S Pyke

A Quintanilha

Affiliations

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Abstract

Our results show that following physical exercise to exhaustion, the levels of reduced glutathione are increased in the plasma, but decreased in both the liver and skeletal muscle of rats. Levels of glutathione disulfide are increased in all 3 tissues. Our results are consistent with a mechanism in which the liver may be dumping reduced glutathione into the plasma in an attempt to deliver it to those tissues that need it the most: in this case, skeletal muscle.

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