Fulminant Parvovirus B19 Myocarditis in Infants -report of Three Post-pandemic Cases

Overview

Journal Eur J Clin Microbiol Infect Dis

Publisher Springer

Specialties Infectious Diseases
Microbiology

Date 2025 Feb 17

PMID 39961949

Authors

Tatjana Wahjudi

Alex Nitsch

Jan-Peter Sperhake

Peter H Hoeger

Affiliations

Soon will be listed here.

Abstract

Lack of immune stimulation ("immune debt") in the wake of the COVID-19 pandemic has led to a resurgence of many paediatric infectious diseases, recently including parvovirus B19 (PVB19). We observed three cases of fulminant PVB19 myocarditis in infants. All had experienced a short prodromal illness and succumbed to cardiogenic shock within 2-72 h after admission. The risk of fulminant myocarditis appears to be increased in infants. Further studies are needed to assess the incidence of fulminant myocarditis caused by PVB19, potentially linked to immune debt.

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