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Antibody-drug Conjugates in Breast Cancer: Advances and Prospects

Overview
Journal Cancer Biol Med
Specialty Oncology
Date 2025 Feb 17
PMID 39960255
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References
1.
Emens L, Esteva F, Beresford M, Saura C, De Laurentiis M, Kim S . Trastuzumab emtansine plus atezolizumab versus trastuzumab emtansine plus placebo in previously treated, HER2-positive advanced breast cancer (KATE2): a phase 2, multicentre, randomised, double-blind trial. Lancet Oncol. 2020; 21(10):1283-1295. DOI: 10.1016/S1470-2045(20)30465-4. View

2.
Hurvitz S, Martin M, Jung K, Huang C, Harbeck N, Valero V . Neoadjuvant Trastuzumab Emtansine and Pertuzumab in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Three-Year Outcomes From the Phase III KRISTINE Study. J Clin Oncol. 2019; 37(25):2206-2216. PMC: 6774816. DOI: 10.1200/JCO.19.00882. View

3.
Sung M, Tan X, Lu B, Golas J, Hosselet C, Wang F . Caveolae-Mediated Endocytosis as a Novel Mechanism of Resistance to Trastuzumab Emtansine (T-DM1). Mol Cancer Ther. 2017; 17(1):243-253. DOI: 10.1158/1535-7163.MCT-17-0403. View

4.
Coates J, Sun S, Leshchiner I, Thimmiah N, Martin E, McLoughlin D . Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer. Cancer Discov. 2021; 11(10):2436-2445. PMC: 8495771. DOI: 10.1158/2159-8290.CD-21-0702. View

5.
Alves F, Gil L, Vasconcelos de Matos L, Baleiras A, Vasques C, Neves M . Impact of Human Epidermal Growth Factor Receptor 2 (HER2) Low Status in Response to Neoadjuvant Chemotherapy in Early Breast Cancer. Cureus. 2022; 14(2):e22330. PMC: 8938239. DOI: 10.7759/cureus.22330. View