Desmoid Fibromatosis Arising from Caecum: an Overview of the Challenges in Diagnosis and Treatment

Desmoid fibromatosis is a rare subtype of soft tissue neoplasms known for its locally aggressive behaviour and fibrotic consistency. While these tumours can arise in various anatomical sites, their occurrence within the colon is exceptionally rare and poses diagnostic and therapeutic challenges. We present a case of a female patient in her 30s with no significant medical history who presented with vague gastrointestinal and urinary symptoms. Imaging studies revealed a sizeable abdominal mass, initially raising uncertainty regarding its origin. Subsequent exploratory laparotomy revealed a desmoid fibromatosis involving the muscularis propria of the caecum, prompting a right hemicolectomy. Histopathological analysis confirmed the diagnosis, and the patient underwent a successful resection with negative margins. This case underscores the importance of individualised treatment plans and long-term surveillance in managing colonic desmoid tumours for optimal outcomes and disease-free survival.