Genetically Modified Crops and Sustainable Development: Navigating Challenges and Opportunities

Overview

Journal Food Sci Biotechnol

Specialty Biotechnology

Date 2025 Feb 13

PMID 39944670

Authors

Rubby Sandhu

Nischay Chaudhary

Rafeeya Shams

Kshirod Kumar Dash

Affiliations

Soon will be listed here.

Abstract

The dominance of Genetically Modified (GM) crops in global agriculture is underscored by the production quantities of GM Maize and GM soybean. This review discusses the global statistics of GM crops mentioning the area of cultivation, production, and adoption rates of GM crops in detail. It relates the comprehensive overview of perception toward GM technology varying across regions, with the younger generation often displaying a preferable outlook. It highlights the environmental benefits of GM crops, explaining the decreased pesticide usage with potential health benefits, and hinting at an indirect decline in cancer occurrences. An overview of advancements in genetic tools have significantly evolved genome editing techniques in agriculture. The use of such tools in the field of agriculture shows promising effects in maintaining sustainable development goals. This review demonstrates that genetic techniques are a responsible and effective tool for generating GM crops to promote sustainable agriculture.

References

Zhang C, Hu R, Huang J, Huang X, Shi G, Li Y . Health effect of agricultural pesticide use in China: implications for the development of GM crops. Sci Rep. 2016; 6:34918. PMC: 5056523. DOI: 10.1038/srep34918. View

Budnik L, Scheer E, Burge P, Baur X . Sensitising effects of genetically modified enzymes used in flavour, fragrance, detergence and pharmaceutical production: cross-sectional study. Occup Environ Med. 2016; 74(1):39-45. DOI: 10.1136/oemed-2015-103442. View

Gassmann A, Reisig D . Management of Insect Pests with Bt Crops in the United States. Annu Rev Entomol. 2022; 68:31-49. DOI: 10.1146/annurev-ento-120220-105502. View

Adrio J, Demain A . Recombinant organisms for production of industrial products. Bioeng Bugs. 2011; 1(2):116-31. PMC: 3026452. DOI: 10.4161/bbug.1.2.10484. View

Georges F, Ray H . Genome editing of crops: A renewed opportunity for food security. GM Crops Food. 2017; 8(1):1-12. PMC: 5592977. DOI: 10.1080/21645698.2016.1270489. View

Zhu F, Jiang T, Wu B, He B . Enhancement of Z-aspartame synthesis by rational engineering of metalloprotease. Food Chem. 2018; 253:30-36. DOI: 10.1016/j.foodchem.2018.01.108. View

Liu L, Iketani S, Guo Y, Chan J, Wang M, Liu L . Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2. Nature. 2022; 602(7898):676-681. DOI: 10.1038/s41586-021-04388-0. View

Boedeker W, Watts M, Clausing P, Marquez E . The global distribution of acute unintentional pesticide poisoning: estimations based on a systematic review. BMC Public Health. 2020; 20(1):1875. PMC: 7720593. DOI: 10.1186/s12889-020-09939-0. View

Janecek S, Svensson B, MacGregor E . α-Amylase: an enzyme specificity found in various families of glycoside hydrolases. Cell Mol Life Sci. 2013; 71(7):1149-70. PMC: 11114072. DOI: 10.1007/s00018-013-1388-z. View

10.

Koukounaras A, Mellidou I, Patelou E, Kostas S, Shukla V, Engineer C . Over-expression of GGP1 and GPP genes enhances ascorbate content and nutritional quality of tomato. Plant Physiol Biochem. 2022; 193:124-138. DOI: 10.1016/j.plaphy.2022.10.023. View

11.

Ewen S, Pusztai A . Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. Lancet. 1999; 354(9187):1353-4. DOI: 10.1016/S0140-6736(98)05860-7. View

12.

Domingo J . Safety assessment of GM plants: An updated review of the scientific literature. Food Chem Toxicol. 2016; 95:12-8. DOI: 10.1016/j.fct.2016.06.013. View

13.

Moller M, Svensson B . Structural biology of starch-degrading enzymes and their regulation. Curr Opin Struct Biol. 2016; 40:33-42. DOI: 10.1016/j.sbi.2016.07.006. View

14.

Schwechheimer S, Park E, Revuelta J, Becker J, Wittmann C . Biotechnology of riboflavin. Appl Microbiol Biotechnol. 2016; 100(5):2107-19. DOI: 10.1007/s00253-015-7256-z. View

15.

Khatodia S, Bhatotia K, Passricha N, Khurana S, Tuteja N . The CRISPR/Cas Genome-Editing Tool: Application in Improvement of Crops. Front Plant Sci. 2016; 7:506. PMC: 4835450. DOI: 10.3389/fpls.2016.00506. View

16.

Martinelli L, Karbarz M, Siipi H . Science, safety, and trust: the case of transgenic food. Croat Med J. 2013; 54(1):91-6. PMC: 3584506. DOI: 10.3325/cmj.2013.54.91. View

17.

Oliver M . Why we need GMO crops in agriculture. Mo Med. 2015; 111(6):492-507. PMC: 6173531. View

18.

Seralini G, Clair E, Mesnage R, Gress S, Defarge N, Malatesta M . Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food Chem Toxicol. 2012; 50(11):4221-31. DOI: 10.1016/j.fct.2012.08.005. View

19.

Trapero C, Wilson I, Stiller W, Wilson L . Enhancing Integrated Pest Management in GM Cotton Systems Using Host Plant Resistance. Front Plant Sci. 2016; 7:500. PMC: 4840675. DOI: 10.3389/fpls.2016.00500. View

20.

Li S, Yang Q, Tang B, Chen A . Improvement of enzymatic properties of Rhizopus oryzae α-amylase by site-saturation mutagenesis of histidine 286. Enzyme Microb Technol. 2018; 117:96-102. DOI: 10.1016/j.enzmictec.2018.06.012. View