Organoid, Organ-on-a-chip and Traditional Chinese Medicine

Overview

Journal Chin Med

Publisher Biomed Central

Specialty Biomedical Engineering

Date 2025 Feb 12

PMID 39940016

Authors

Jiayue Yang

Yu Jiang

Mingxing Li

Ke Wu

Shulin Wei

Yueshui Zhao

Jing Shen

Fukuan Du

Yu Chen

Shuai Deng

Zhangang Xiao

Wen Yuan

Xu Wu

Affiliations

Soon will be listed here.

Abstract

In the past few years, the emergence of organoids and organ-on-a-chip (OOAC) technologies, which are complementary to animal models and two-dimensional cell culture methods and can better simulate the internal environment of the human body, provides a new platform for traditional Chinese medicine (TCM) studies. Organoids and OOAC techniques have been increasingly applied in the fields of drug screening, drug assessment and development, personalized therapies, and developmental biology, and there have been some application cases in the TCM studies. In this review, we summarized the current status of using organoid and OOAC technologies in TCM research and provide key insights for future study. It is believed that organoid and OOAC technologies will play more and more important roles in research and make greater contributions to the innovative development of TCM.

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