Capsule Endoscopy: Do We Still Need It After 24 Years of Clinical Use?

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Date 2025 Feb 10

PMID 39926220

Authors

Ahmed Tawheed

Alaa Ismail

Mohab S Amer

Osama Elnahas

Tawhid Mowafy

Affiliations

Soon will be listed here.

Abstract

In this letter, we comment on a recent article published in the by Xiao , where the authors aimed to use a deep learning model to automatically detect gastrointestinal lesions during capsule endoscopy (CE). CE was first presented in 2000 and was approved by the Food and Drug Administration in 2001. The indications of CE overlap with those of regular diagnostic endoscopy. However, in clinical practice, CE is usually used to detect lesions in areas inaccessible to standard endoscopies or in cases of bleeding that might be missed during conventional endoscopy. Since the emergence of CE, many physiological and technical challenges have been faced and addressed. In this letter, we summarize the current challenges and briefly mention the proposed methods to overcome these challenges to answer a central question: Do we still need CE?

References

Alaskar H, Hussain A, Al-Aseem N, Liatsis P, Al-Jumeily D . Application of Convolutional Neural Networks for Automated Ulcer Detection in Wireless Capsule Endoscopy Images. Sensors (Basel). 2019; 19(6). PMC: 6471286. DOI: 10.3390/s19061265. View

Pennazio M, Spada C, Eliakim R, Keuchel M, May A, Mulder C . Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy. 2015; 47(4):352-76. DOI: 10.1055/s-0034-1391855. View

Hale M, Sidhu R, McAlindon M . Capsule endoscopy: current practice and future directions. World J Gastroenterol. 2014; 20(24):7752-9. PMC: 4069303. DOI: 10.3748/wjg.v20.i24.7752. View

Triester S, Leighton J, Leontiadis G, Fleischer D, Hara A, Heigh R . A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding. Am J Gastroenterol. 2005; 100(11):2407-18. DOI: 10.1111/j.1572-0241.2005.00274.x. View

Hassan A, Haque M . Computer-aided gastrointestinal hemorrhage detection in wireless capsule endoscopy videos. Comput Methods Programs Biomed. 2015; 122(3):341-53. DOI: 10.1016/j.cmpb.2015.09.005. View

Wang A, Banerjee S, Barth B, Bhat Y, Chauhan S, Gottlieb K . Wireless capsule endoscopy. Gastrointest Endosc. 2013; 78(6):805-815. DOI: 10.1016/j.gie.2013.06.026. View

Pennazio M . Capsule endoscopy: where are we after 6 years of clinical use?. Dig Liver Dis. 2006; 38(12):867-78. DOI: 10.1016/j.dld.2006.09.007. View

Le Berre C, Sandborn W, Aridhi S, Devignes M, Fournier L, Smail-Tabbone M . Application of Artificial Intelligence to Gastroenterology and Hepatology. Gastroenterology. 2019; 158(1):76-94.e2. DOI: 10.1053/j.gastro.2019.08.058. View

Li B, Meng M . Tumor recognition in wireless capsule endoscopy images using textural features and SVM-based feature selection. IEEE Trans Inf Technol Biomed. 2012; 16(3):323-9. DOI: 10.1109/TITB.2012.2185807. View

10.

Leung B, Poon C, Zhang R, Zheng Y, Chan C, Chiu P . A Therapeutic Wireless Capsule for Treatment of Gastrointestinal Haemorrhage by Balloon Tamponade Effect. IEEE Trans Biomed Eng. 2016; 64(5):1106-1114. DOI: 10.1109/TBME.2016.2591060. View

11.

Fritscher-Ravens A, Scherbakov P, Bufler P, Torroni F, Ruuska T, Nuutinen H . The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study. Gut. 2009; 58(11):1467-72. DOI: 10.1136/gut.2009.177774. View

12.

Cao Q, Deng R, Pan Y, Liu R, Chen Y, Gong G . Robotic wireless capsule endoscopy: recent advances and upcoming technologies. Nat Commun. 2024; 15(1):4597. PMC: 11139981. DOI: 10.1038/s41467-024-49019-0. View

13.

Kim H, Yang S, Kim J, Park S, Cho J, Park J . Active locomotion of a paddling-based capsule endoscope in an in vitro and in vivo experiment (with videos). Gastrointest Endosc. 2010; 72(2):381-7. DOI: 10.1016/j.gie.2009.12.058. View

14.

Han S, Fahed J, Cave D . Suspected Blood Indicator to Identify Active Gastrointestinal Bleeding: A Prospective Validation. Gastroenterology Res. 2018; 11(2):106-111. PMC: 5916634. DOI: 10.14740/gr949w. View

15.

Zhou T, Han G, Li B, Lin Z, Ciaccio E, Green P . Quantitative analysis of patients with celiac disease by video capsule endoscopy: A deep learning method. Comput Biol Med. 2017; 85:1-6. DOI: 10.1016/j.compbiomed.2017.03.031. View

16.

Yuan Y, Wang J, Li B, Meng M . Saliency based ulcer detection for wireless capsule endoscopy diagnosis. IEEE Trans Med Imaging. 2015; 34(10):2046-57. DOI: 10.1109/TMI.2015.2418534. View

17.

Miah O, Hossain R, Latif A, Sarkar U, Paul S, Paul R . Pattern of Anaemia in Chronic Kidney Disease. Mymensingh Med J. 2019; 28(1):1-7. View

18.

Zhuang H, Wang W, Zhao K, Fei Q, Yan G . Design and analysis of a wireless power transfer system for capsule robot using an optimised planar square spiral transmitting coil pair. Int J Med Robot. 2022; 18(4):e2399. DOI: 10.1002/rcs.2399. View

19.

Pasha S, Leighton J, Das A, Harrison M, Decker G, Fleischer D . Double-balloon enteroscopy and capsule endoscopy have comparable diagnostic yield in small-bowel disease: a meta-analysis. Clin Gastroenterol Hepatol. 2008; 6(6):671-6. DOI: 10.1016/j.cgh.2008.01.005. View

20.

Kopylov U, Seidman E . Diagnostic modalities for the evaluation of small bowel disorders. Curr Opin Gastroenterol. 2015; 31(2):111-7. DOI: 10.1097/MOG.0000000000000159. View