Mycoparasitic Transcription Factor 1 (BcMTF1) Participates in the Response Against

Overview

Journal iScience

Publisher Cell Press

Date 2025 Feb 10

PMID 39925430

Authors

Consuelo Olivares-Yanez

Nicolas Arias-Inostroza

Ruben Polanco

Paulo Canessa

Affiliations

Soon will be listed here.

Abstract

is a phytopathogenic fungus. Traditional control using fungicides has faced challenges, prompting the exploration of sustainable alternatives such as biocontrol. , a promising biocontroller, is well-known for its mycoparasitism. However, the molecular processes involved in this fungal-fungal interaction, particularly regarding the defense mechanisms of the pathogen, have yet to be deeply studied. Here, we investigated the transcriptional defense responses of to . We focused on four transcription factors (TFs) differentially expressed during interaction with the biocontroller. Mutants lacking these TFs exhibit increased sensitivity to , with the Bcin07g06800 (BcMTF1) loss-of-function mutant being most susceptible. Genes predicted to be regulated by mycoparasitic transcription factor 1 were differentially expressed during this interaction. BcMTF1 influences 's resistance to mycoparasitism by regulating the expression of genes potentially involved in fungal defense against . The findings provide insights into the transcriptional processes underlying fungal-fungal interactions.

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