Individual Variability in Lactate Response to Cycling Prescribed Using Physiological Thresholds and Peak Work Rate: a Crossover Within-participant Repeated Measures Study

Overview

Journal Eur J Appl Physiol

Date 2025 Feb 5

PMID 39907774

Authors

Lauren J Pacitti

Kaitlyn E Shikaze

Nia Simpson-Stairs

Jonathan Stringer

Brendon J Gurd

Affiliations

Soon will be listed here.

Abstract

Purpose: (1) To determine if the blood lactate concentration ([BLa]) response is a repeatable individual trait, and (2) To examine whether threshold-based prescription (THR) reduces interindividual variability in [BLa] response compared to traditional (maximally anchored) exercise prescription (TRAD).

Method: A crossover within-participant repeated measures design was used to assess [BLa] during the TRAD and THR exercise in 17 participants (9 M/8F). Participants initially undertook an incremental test to exhaustion to determine peak work rate (WRpeak), a lactate threshold (LT) test and a critical power (CP) test. All baseline tests were repeated twice. Participants then completed 6 15-min bouts of continuous cycling at 65%WRpeak (TRAD; 3 bouts) and 80% of the difference (Δ80) between LT and CP (THR; 3 bouts). [BLa] response was measured at 10 and 15 min of exercise.

Results: Across individuals, there was a wide range in [BLa] response, but within individual responses were repeatable. [BLa] ranges and mean individual 90% confidence interval width (CI) were as follows: TRAD@10 min = 2.1-9.7 mmol, CI = 0.5 mmol, THR@10 min = 3.4-9.3 mmol, CI = 0.6 mmol, TRAD@15 min = 2.2-9.9 mmol, CI = 0.6 mmol, THR@15 min = 3.6-12.3 mmol, CI = 0.7 mmol. Levene's tests revealed no significant differences in the variability of [BLa] response between TRAD and THR at 10 min (F = 0.523, p = 0.475) or 15 min (F = 0.351, p = 0.558) of exercise.

Conclusion: Our results demonstrate that true interindividual variability in the [BLa] response to exercise exists, but failed to confirm that variability in [BLa] response is reduced with the use of THR.

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