The Role of Platelet-rich Plasma in Biomedicine: A Comprehensive Overview

Overview

Journal iScience

Publisher Cell Press

Date 2025 Feb 3

PMID 39898035

Authors

Zhixin Zhang

Peng Liu

Xinmiao Xue

Zhiyu Zhang

Li Wang

Yvke Jiang

Chi Zhang

Hanwen Zhou

Shuhan Lv

Weidong Shen

Shiming Yang

Fangyuan Wang

Affiliations

Soon will be listed here.

Abstract

Biomedicine has seen significant advancements in the 21st century, with platelet-rich plasma (PRP) playing a crucial role in clinical practice. This blood derivative, enriched with platelet components, has shown great potential for promoting tissue repair and regeneration. Its wide range of applications and the presence of anti-inflammatory and growth-promoting factors make it a valuable tool in the field of biomedicine. The exploration of PRP in clinical settings has been gaining momentum. Despite its cost-effectiveness, safety, and therapeutic efficacy, the widespread clinical adoption of PRP has been hindered by the absence of consistent preparation standards and standardized treatment protocols. This article provides a comprehensive analysis of the clinical uses, physiological roles, molecular mechanisms, and preparation techniques of PRP in biomedicine. The aim is to offer a thorough understanding of the potential applications and benefits of PRP in medical practice.

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