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A 675 Nm Laser in the Treatment of Facial Melasma in Dark Skin Types

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Date 2025 Feb 3
PMID 39895335
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Abstract

Melasma therapy can be difficult and requires employing different treatment approaches. Laser therapy is a good alternative for treating melasma, especially for patients with refractory cases. To evaluate the efficacy and safety of newcomer wavelength 675 nm diode laser in treating melasma in darker skin types. Nineteen female patients with facial melasma were recruited. They received four sessions of 675 nm laser at one-month intervals using the following parameters: power 5-6 W, pulse duration 100-150 ms, spacing 2000 mm, and stack one up to 4 passes. One month after the last treatment session, the evaluation was done subjectively through the modified melasma area and severity index (mMASI) score and objectively using the Antera 3D camera. After treatment, there was a highly statistically significant reduction in mMASI scores. In addition, the scores on the Antera camera recorded highly statistically significant differences in the treated areas' melanin and hemoglobin average levels. The novel 675 nm laser represents a safe and efficient approach in treating melasma in darker phototype patients.