» Articles » PMID: 39894039

Management of Elderly Patients with Chronic Kidney Disease

Overview
Journal Yonsei Med J
Date 2025 Feb 2
PMID 39894039
Authors
Affiliations
Soon will be listed here.
Abstract

Chronic kidney disease (CKD) is highly prevalent among elderly patients, and as the global population ages, the number of elderly patients with CKD is increasing. Elderly patients require additional considerations beyond those required for their younger counterparts, such as comorbidities, frailty, and geriatric syndromes. In this review, we primarily focus on these additional considerations specific to elderly patients and discuss the assessment of CKD and its management strategies, including blood pressure and glycemic control; dyslipidemia, anemia, and electrolyte and metabolic acidosis management; and medication dosage, among others, as well as polypharmacy and nonpharmacological management. Furthermore, the concept of conservative kidney management and the practical recommendations of the Korean Society of Geriatric Nephrology for elderly patients with end-stage kidney disease requiring dialysis therapy are discussed. In particular, the aging rate in Korea is exceptionally high; therefore, it is crucial to pay more attention to the increase in elderly patients with CKD. A more palliative approach, rather than intensive treatment strategies, may be necessary for these patients. In a world with an abundance of information, shared decision-making with patients is of great importance, and it is essential to keep in mind that this holds true for elderly patients as well.

References
1.
Heerspink H, Stefansson B, Correa-Rotter R, Chertow G, Greene T, Hou F . Dapagliflozin in Patients with Chronic Kidney Disease. N Engl J Med. 2020; 383(15):1436-1446. DOI: 10.1056/NEJMoa2024816. View

2.
Wong S, Oestreich T, Chandler B, Curtis J . Using Human-Centered Design Principles to Create a Decision Aid on Conservative Kidney Management for Advanced Kidney Disease. Kidney360. 2022; 3(7):1242-1252. PMC: 9337892. DOI: 10.34067/KID.0000392022. View

3.
Inouye S, Studenski S, Tinetti M, Kuchel G . Geriatric syndromes: clinical, research, and policy implications of a core geriatric concept. J Am Geriatr Soc. 2007; 55(5):780-91. PMC: 2409147. DOI: 10.1111/j.1532-5415.2007.01156.x. View

4.
McGonigle R, Wallin J, Shadduck R, Fisher J . Erythropoietin deficiency and inhibition of erythropoiesis in renal insufficiency. Kidney Int. 1984; 25(2):437-44. DOI: 10.1038/ki.1984.36. View

5.
Zhou Z, Albarqouni L, Breslin M, Curtis A, Nelson M . Statin-associated muscle symptoms (SAMS) in primary prevention for cardiovascular disease in older adults: a protocol for a systematic review and meta-analysis of randomised controlled trials. BMJ Open. 2017; 7(9):e017587. PMC: 5623566. DOI: 10.1136/bmjopen-2017-017587. View