Differences in Body Composition, Bone Density, and Tibial Microarchitecture in Division I Female Athletes Participating in Different Impact Loading Sports

Overview

Journal Calcif Tissue Int

Date 2025 Jan 29

PMID 39881030

Authors

Kelly H Mroz

Adam J Sterczala

Nicole M Sekel

Mita Lovalekar

Pouneh K Fazeli

Jane A Cauley

Thomas J OLeary

Julie P Greeves

Bradley C Nindl

Kristen J Koltun

Affiliations

Soon will be listed here.

Abstract

Sport participation affects body composition and bone health, but the association between sport, body composition, and bone health in female athletes is complex. We compared areal bone mineral density (aBMD, DXA) and tibial volumetric bone mineral density (vBMD), geometry, microarchitecture, and estimated strength (HR-pQCT) in cross-country runners (n = 22), gymnasts (n = 23) and lacrosse players (n = 35), and investigated associations of total body lean mass (TBLM), team, and their interaction with tibial bone outcomes. Total body (TB), total hip (TH), femoral neck (FN), and lumbar spine (LS) aBMD were higher in gymnasts than runners (p < 0.001); FN and LS aBMD were higher in gymnasts than lacrosse players (p ≤ 0.045); and TB, TH, FN, and LS aBMD were higher in lacrosse players than runners (p ≤ 0.013). At the distal tibial metaphysis, total area (Tt.Ar) was higher in gymnasts than runners (p = 0.004); cortical area and thickness (Ct.Ar, Ct.Th) were higher in lacrosse players than runners (p ≤ 0.044); trabecular separation (Tb.Sp) was higher in runners than gymnasts (p = 0.031); and failure load was higher in both gymnasts and lacrosse players than runners (p ≤ 0.012). At the tibial diaphysis, Tt.Ar, Ct.Ar, cortical perimeter (Ct.Pm), and failure load were higher in gymnasts than runners (p ≤ 0.040). In multiple linear regression analyses, TBLM was significantly associated with metaphyseal failure load (ß = 0.30, p = 0.042), and diaphyseal Tt.Ar and Ct.Pm (ß = 6.17, p = 0.003; ß = 0.59, p = 0.010). Bone health can vary among different sport types and is associated with TBLM, which may be a modifiable factor to maintain or improve bone health.

References

Koltun K, Sekel N, Bird M, Lovalekar M, Mi Q, Martin B . Tibial Bone Geometry Is Associated With Bone Stress Injury During Military Training in Men and Women. Front Physiol. 2022; 13:803219. PMC: 8874318. DOI: 10.3389/fphys.2022.803219. View

Wade S, Strader C, Fitzpatrick L, Anthony M, OMalley C . Estimating prevalence of osteoporosis: examples from industrialized countries. Arch Osteoporos. 2014; 9:182. DOI: 10.1007/s11657-014-0182-3. View

McCormack W, Shoepe T, LaBrie J, Almstedt H . Bone mineral density, energy availability, and dietary restraint in collegiate cross-country runners and non-running controls. Eur J Appl Physiol. 2019; 119(8):1747-1756. PMC: 10496742. DOI: 10.1007/s00421-019-04164-z. View

Schipilow J, Macdonald H, Liphardt A, Kan M, Boyd S . Bone micro-architecture, estimated bone strength, and the muscle-bone interaction in elite athletes: an HR-pQCT study. Bone. 2013; 56(2):281-9. DOI: 10.1016/j.bone.2013.06.014. View

Nikander R, Kannus P, Rantalainen T, Uusi-Rasi K, Heinonen A, Sievanen H . Cross-sectional geometry of weight-bearing tibia in female athletes subjected to different exercise loadings. Osteoporos Int. 2009; 21(10):1687-94. DOI: 10.1007/s00198-009-1101-0. View

Greene D, Naughton G, Bradshaw E, Moresi M, Ducher G . Mechanical loading with or without weight-bearing activity: influence on bone strength index in elite female adolescent athletes engaged in water polo, gymnastics, and track-and-field. J Bone Miner Metab. 2012; 30(5):580-7. DOI: 10.1007/s00774-012-0360-6. View

Hughes J, Popp K, Yanovich R, Bouxsein M, Matheny Jr R . The role of adaptive bone formation in the etiology of stress fracture. Exp Biol Med (Maywood). 2016; 242(9):897-906. PMC: 5407583. DOI: 10.1177/1535370216661646. View

Turner C, Robling A . Designing exercise regimens to increase bone strength. Exerc Sport Sci Rev. 2003; 31(1):45-50. DOI: 10.1097/00003677-200301000-00009. View

Turner C . Three rules for bone adaptation to mechanical stimuli. Bone. 1998; 23(5):399-407. DOI: 10.1016/s8756-3282(98)00118-5. View

10.

Hert J, Liskova M, Landa J . Reaction of bone to mechanical stimuli. 1. Continuous and intermittent loading of tibia in rabbit. Folia Morphol (Praha). 1971; 19(3):290-300. View

11.

Hughes J, OLeary T, Koltun K, Greeves J . Promoting adaptive bone formation to prevent stress fractures in military personnel. Eur J Sport Sci. 2021; 22(1):4-15. DOI: 10.1080/17461391.2021.1949637. View

12.

Bemben D, Buchanan T, Bemben M, Knehans A . Influence of type of mechanical loading, menstrual status, and training season on bone density in young women athletes. J Strength Cond Res. 2004; 18(2):220-6. DOI: 10.1519/R-12652.1. View

13.

Warden S, Sventeckis A, Surowiec R, Fuchs R . Enhanced Bone Size, Microarchitecture, and Strength in Female Runners with a History of Playing Multidirectional Sports. Med Sci Sports Exerc. 2022; 54(12):2020-2030. PMC: 9669197. DOI: 10.1249/MSS.0000000000003016. View

14.

Rizzone K, Ackerman K, Roos K, Dompier T, Kerr Z . The Epidemiology of Stress Fractures in Collegiate Student-Athletes, 2004-2005 Through 2013-2014 Academic Years. J Athl Train. 2017; 52(10):966-975. PMC: 5687241. DOI: 10.4085/1062-6050-52.8.01. View

15.

Zabriskie H, Currier B, Harty P, Stecker R, Jagim A, Kerksick C . Energy Status and Body Composition Across a Collegiate Women's Lacrosse Season. Nutrients. 2019; 11(2). PMC: 6412364. DOI: 10.3390/nu11020470. View

16.

Tenforde A, Carlson J, Chang A, Sainani K, Shultz R, Kim J . Association of the Female Athlete Triad Risk Assessment Stratification to the Development of Bone Stress Injuries in Collegiate Athletes. Am J Sports Med. 2016; 45(2):302-310. DOI: 10.1177/0363546516676262. View

17.

Dobrosielski D, Leppert K, Knuth N, Wilder J, Kovacs L, Lisman P . Body Composition Values of NCAA Division 1 Female Athletes Derived From Dual-Energy X-Ray Absorptiometry. J Strength Cond Res. 2019; 35(10):2886-2893. DOI: 10.1519/JSC.0000000000003213. View

18.

Matijevich E, Branscombe L, Scott L, Zelik K . Ground reaction force metrics are not strongly correlated with tibial bone load when running across speeds and slopes: Implications for science, sport and wearable tech. PLoS One. 2019; 14(1):e0210000. PMC: 6336327. DOI: 10.1371/journal.pone.0210000. View

19.

Hamrick M . The skeletal muscle secretome: an emerging player in muscle-bone crosstalk. Bonekey Rep. 2013; 1:60. PMC: 3727847. DOI: 10.1038/bonekey.2012.60. View

20.

Warden S, Edwards W, Willy R . Preventing Bone Stress Injuries in Runners with Optimal Workload. Curr Osteoporos Rep. 2021; 19(3):298-307. PMC: 8316280. DOI: 10.1007/s11914-021-00666-y. View