Changes in Brush-border Enzyme Activities of Intestinal Epithelial Cells Isolated from the Villus-crypt Axis During the Early Phase of Alloxan Diabetes in Rats
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Abstract
The sucrase activity in enterocytes isolated from the villus crypt axis was found to increase in all regions of the villus from day 2 after induction of diabetes, and the increase continued until day 4. In contrast, alkaline phosphatase activity increased mainly in the apical one-third of the villus-crypt column, and the increase occurred abruptly on day 4 with increase in food intake.
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Miguez I, Marino G, Rodriguez B, Taboada C J Physiol Biochem. 2004; 60(1):31-7.
PMID: 15352382 DOI: 10.1007/BF03168218.
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