Essential and Risk Elements in Horses Affect Haematology, Serum Biochemistry and Oxidative Status Parameters

Overview

Journal Sci Rep

Date 2025 Jan 28

PMID 39875518

Authors

Marko Halo Jr

Robert Kirchner

Filip Tirpak

Tomas Slanina

Katarina Tokarova

Anton Kovacik

Michal Miskeje

Agnieszka Gren

Grzegorz Formicki

Marko Halo

Roberto Madeddu

Peter Massanyi

Affiliations

Soon will be listed here.

Abstract

The abundance of chemical elements in the blood of horses can indicate the physiological balance, health of animal as well as can be taken as an indicator of environmental pollution. The aim of this work was to analyse haematological, biochemical parameters, TOS, FRAP, SOD, Gpx, TAS and their correlations with concentrations of essential and risk elements in blood of horses stabled in two different locations: The National Stud Farm Topoľčianky (n = 11; 11 stallions, consisting of the breeds 6 Lipizzan, 3 Slovak warmblood, 2 Holsteiner) and Experimental Centre at Institute of Animal Husbandry, SUA in Nitra (n = 10; 4 stallions, 5 geldings, 1 mare, 4 stallions, 5 geldings and 1 mare, consisting of the breeds 3 Slovak warmblood, 4 Czech warmblood, 3 Holsteiner). Blood samples were obtained from horses (n = 21) from two localities in the Slovak Republic during May. The haematological profiles of horses from both locations were within reference values. The values of biochemical parameters of horse samples that underwent analysis showed only minor deviations from the referential values reported by several authors. Fe was the most accumulated elements (383.95 mg/L and 403.61 mg/L, respectively). Finally, this investigation based on correlation analyses identified essential and risk elements in horse blood serum and significant negative correlation between Cd and GRA, HGB and HCT was observed in The National Stud Farm Topoľčianky and a positive correlation was recorded between Zn and total proteins in the Experimental Centre at Institute of Animal Husbandry, SUA Nitra. The obtained data could be used as a control indicator to identify risk hazards related to the heavy metals in relation to the health of animals.

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