Intraventricular Tumors in Tuberous Sclerosis

Overview

Journal Childs Nerv Syst

Specialty Pediatrics

Date 1985 Jan 1

PMID 3986841

Citations 14

Authors

P Frerebeau

J Benezech

F Segnarbieux

H Harbi

A Desy

C Marty-Double

Affiliations

Soon will be listed here.

Abstract

Eleven of our own cases of tuberous sclerosis with intraventricular tumor and 34 cases from the literature are reviewed. Initial symptoms and identification of tuberous sclerosis and tumor are reviewed. Results of surgical treatment, including direct radical excision and shunting are given. On gross examination, the tumor was most often loosely connected to ependyma near the foramen of Monro, causing hydrocephalus. Giant cell subependymal astrocytoma was frequently found on microscopic examination. The glial origin of the tumor is discussed and direct surgical approach of the tumor is proposed as the best treatment of these lesions.

Citing Articles

Current trends in the management of subependymal giant cell astrocytomas in tuberous sclerosis.

Frassanito P, Noya C, Tamburrini G Childs Nerv Syst. 2020; 36(10):2527-2536.

PMID: 32978642 DOI: 10.1007/s00381-020-04889-9.

Neurosurgical treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex: a series of 44 surgical procedures in 31 patients.

Giordano F, Moscheo C, Lenge M, Biagiotti R, Mari F, Sardi I Childs Nerv Syst. 2019; 36(5):951-960.

PMID: 31853898 DOI: 10.1007/s00381-019-04449-w.

Surgery for subependymal giant cell astrocytomas in children with tuberous sclerosis complex.

Fohlen M, Ferrand-Sorbets S, Delalande O, Dorfmuller G Childs Nerv Syst. 2018; 34(8):1511-1519.

PMID: 29766265 DOI: 10.1007/s00381-018-3826-6.

TSC1 and TSC2 gene mutations and their implications for treatment in Tuberous Sclerosis Complex: a review.

Rosset C, Oliveira Netto C, Ashton-Prolla P Genet Mol Biol. 2017; 40(1):69-79.

PMID: 28222202 PMC: 5409767. DOI: 10.1590/1678-4685-GMB-2015-0321.

Clinicopathoradiological findings in SEGA: A rare astroglial tumor.

Verma N, Babu S, Singhai A, Gupta C Indian J Med Paediatr Oncol. 2012; 33(3):192-3.

PMID: 23248435 PMC: 3523486. DOI: 10.4103/0971-5851.103158.

References

Lee B, Gawler J . Tuberous sclerosis. Comparison of computed tomography and conventional neuroradiology. Radiology. 1978; 127(2):403-7. DOI: 10.1148/127.2.403. View

Herz D, LIEBESKIND A, DIXON G, SCHECHTER M . Cerebral angiographic changes associated with tuberous sclerosis. Radiology. 1975; 115(3):647-9. DOI: 10.1148/15.3.647. View

REED W, NICKEL W, Campion G . Internal manifestations of tuberous sclerosis. Arch Dermatol. 1963; 87:715-28. DOI: 10.1001/archderm.1963.01590180043009. View

TOGA M, Dubois D, Berard M, Tripier M, Cesarini J, Choux R . [Ultrastructural study of 4 cases of subacute sclerosing leukoencephalitis]. Acta Neuropathol. 1969; 14(1):1-13. DOI: 10.1007/BF00687698. View

RUDNICK P, Hoshino N, Kitaoka T, MIURAM . Tuberous sclerosis complex and astrocytoma. Report of a case with successful removal of the neoplasm. JAMA. 1961; 178:73-5. DOI: 10.1001/jama.1961.73040400026017d. View

Tsuchida T, Kamata K, Kawamata M, Okada K, Tanaka R, OYAKE Y . Brain tumors in tuberous sclerosis. Report of 4 cases. Childs Brain. 1981; 8(4):271-83. DOI: 10.1159/000119990. View

TAPTAS J, Kordiolis N, Charalambopoulos F . [Tumoral forms of tuberous sclerosis. The clinical and therapeutic importance of concomitant hydrocephalus (author's transl)]. Neurochirurgie. 1978; 24(2):113-6. View

Boesel C, PAULSON G, Kosnik E, EARLE K . Brain hamartomas and tumors associated with tuberous sclerosis. Neurosurgery. 1979; 4(5):410-7. DOI: 10.1227/00006123-197905000-00006. View

Cooper J . Brain tumors in hereditary multiple system hamartomatosis (tuberous sclerosis). J Neurosurg. 1971; 34(2 Pt 1):194-202. DOI: 10.3171/jns.1971.34.2part1.0194. View

10.

Sima A, Robertson D . Subependymal giant-cell astrocytoma. Case report with ultrastructural study. J Neurosurg. 1979; 50(2):240-5. DOI: 10.3171/jns.1979.50.2.0240. View

11.

Kapp J, PAULSON G, ODOM G . Brain tumors with tuberous sclerosis. J Neurosurg. 1967; 26(2):191-202. DOI: 10.3171/jns.1967.26.2.0191. View

12.

Marty-Double C, Dememes D, Marty R . [Intraventricular glial tumor. in the evolution of Bourneville tuberous sclerosis: ultrastructural study]. Ann Anat Pathol (Paris). 1976; 21(3):329-38. View

13.

Monaghan H, Krafchik B, MacGregor D, Fitz C . Tuberous sclerosis complex in children. Am J Dis Child. 1981; 135(10):912-7. DOI: 10.1001/archpedi.1981.02130340024010. View

14.

Dumas J, Poirier J, ESCOUROLLE R . [Ultrastructural study of cerebral lesions in tuberous sclerosis (author's transl)]. Acta Neuropathol. 1973; 25(4):259-70. DOI: 10.1007/BF00691754. View

15.

Kessel F . Some radiological and neurosurgical aspects of tuberous sclerosis. Acta Psychiatr Neurol. 1949; 24(3-4):499-522. DOI: 10.1111/j.1600-0447.1949.tb07335.x. View

16.

Fitz C, Harwood-Nash D, Thompson J . Neuroradiology of tuberous sclerosis in children. Radiology. 1974; 110(3):635-42. DOI: 10.1148/110.3.635. View

17.

Brown J . Tuberose sclerosis with malignant astrocytoma. Med J Aust. 1975; 1(26):811-4. DOI: 10.5694/j.1326-5377.1975.tb82053.x. View

18.

PAILLAS J, PELLEGRIN J, VIGOUROUX R, Serratrice G . [Brain tumors in tuberous sclerosis of Bourneville]. Presse Med (1893). 1954; 62(63):1293-6. View

19.

Pampiglione G, Pugh E . Letter: Infantile spasms and subsequent appearance of tuberous sclerosis syndrome. Lancet. 1975; 2(7943):1046. DOI: 10.1016/s0140-6736(75)90343-8. View

20.

Pellissier J, Tripier M, BERARD-BADIER M, TOGA M . [Ultrastructural study of a tumor of the caudate nucleus in a case of Bourneville's disease]. Arch Anat Pathol (Paris). 1972; 20(3):277-84. View