Irreversible Electroporation for Metastatic Pancreatic Carcinoma with Liver Metastasis: What Does the Evidence Say

Overview

Journal World J Clin Cases

Publisher Baishideng Publishing Group

Date 2025 Jan 27

PMID 39866648

Authors

Ranit Seal

Akash Bararia

Bitan Kumar Chattopadhyay

Nilabja Sikdar

Affiliations

Soon will be listed here.

Abstract

Irreversible electroporation is a promising non-thermal ablation method that has been shown to increase overall survival in locally advanced pancreatic cancer in some studies. However, higher quality studies with proper controls and randomization are required to establish its superiority when added with neoadjuvant chemotherapy over the current management of choice, which is chemotherapy alone. Further studies are required before establishment of any survival benefit in metastatic pancreatic carcinoma, and such evidence is lacking at present.

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