Relative Validity of the Groningen IBD Nutritional Questionnaire (GINQ-FFQ): A Food Frequency Questionnaire Designed to Assess Nutritional Intake in Patients with Inflammatory Bowel Disease

Overview

Journal Nutrients

Date 2025 Jan 25

PMID 39861369

Authors

Iris Barth

Corien L Stevens

Vera Peters

Desiree A Lucassen

Edith J M Feskens

Gerard Dijkstra

Marjo J E Campmans-Kuijpers

Affiliations

Soon will be listed here.

Abstract

To assess nutritional intake of patients with inflammatory bowel disease (IBD), a disease-specific food frequency questionnaire (FFQ) was developed: the Groningen IBD Nutritional Questionnaire (GINQ-FFQ). Aim of this study was to assess the relative validity of the GINQ-FFQ. Between 2019 and 2022, participants of the 1000IBD cohort were included and filled out a 3-day food diary and the GINQ-FFQ. Nutritional intake of nutrients and food groups was calculated. Bland-Altman analysis was conducted for energy intake, while paired -tests and Wilcoxon signed rank tests were used for nutrient and food group intake. Additionally, group-level bias, cross-classification, and correlation analysis were performed. 142 patients (59.2% females, mean age of 49 ± 14 years) were included. Bland-Altman analysis showed a mean difference between the GINQ-FFQ and 3FD of -63.6 kcal (±638.4), with limits of agreement ranging from -1315 to 1188 kcal. Differences in energy intake was significantly associated with higher mean total energy intake ( < 0.001). When stratifying for sex, this association only was significant for males. Group-level bias showed that the GINQ-FFQ tends to result in lower intake reports for macro- and micronutrients. Ranking ability (cross-classification) of macro-, micronutrients and food groups was good. Correlation coefficients for nutrients and food groups were considered acceptable or good. Overall, the GINQ-FFQ is a valid food frequency questionnaire to assess nutritional intake specifically for patients with IBD. However, for males with high total energy intakes, dietary assessment could be less accurate.

References

Rossi R, Whyand T, Murray C, Hamilton M, Conte D, Caplin M . The role of dietary supplements in inflammatory bowel disease: a systematic review. Eur J Gastroenterol Hepatol. 2016; 28(12):1357-1364. DOI: 10.1097/MEG.0000000000000728. View

Masson L, McNeill G, Tomany J, Simpson J, Peace H, Wei L . Statistical approaches for assessing the relative validity of a food-frequency questionnaire: use of correlation coefficients and the kappa statistic. Public Health Nutr. 2003; 6(3):313-21. DOI: 10.1079/PHN2002429. View

Hebert J, Ma Y, Clemow L, Ockene I, Saperia G, Stanek 3rd E . Gender differences in social desirability and social approval bias in dietary self-report. Am J Epidemiol. 1998; 146(12):1046-55. DOI: 10.1093/oxfordjournals.aje.a009233. View

Christ A, Latz E . The Western lifestyle has lasting effects on metaflammation. Nat Rev Immunol. 2019; 19(5):267-268. DOI: 10.1038/s41577-019-0156-1. View

Talmon J, Ros M, Legemate D . PSI: The Dutch Academic Infrastructure for shared biobanks for translational research. Summit Transl Bioinform. 2011; 2008:110-4. PMC: 3041528. View

Siebelink E, Geelen A, de Vries J . Self-reported energy intake by FFQ compared with actual energy intake to maintain body weight in 516 adults. Br J Nutr. 2011; 106(2):274-81. DOI: 10.1017/S0007114511000067. View

Neelakantan N, Whitton C, Seah S, Koh H, Rebello S, Lim J . Development of a Semi-Quantitative Food Frequency Questionnaire to Assess the Dietary Intake of a Multi-Ethnic Urban Asian Population. Nutrients. 2016; 8(9). PMC: 5037515. DOI: 10.3390/nu8090528. View

Fernandez A, Omar S, Husain R . Development and validation of a food frequency questionnaire to estimate the intake of genistein in Malaysia. Int J Food Sci Nutr. 2013; 64(7):794-800. DOI: 10.3109/09637486.2013.798269. View

Brouwer-Brolsma E, Perenboom C, Sluik D, van de Wiel A, Geelen A, Feskens E . Development and external validation of the 'Flower-FFQ': a FFQ designed for the Lifelines Cohort Study. Public Health Nutr. 2021; 25(2):225-236. PMC: 8883771. DOI: 10.1017/S1368980021002111. View

10.

Hughes L, King L, Morgan M, Ayis S, Direkze N, Lomer M . Food-related Quality of Life in Inflammatory Bowel Disease: Development and Validation of a Questionnaire. J Crohns Colitis. 2015; 10(2):194-201. DOI: 10.1093/ecco-jcc/jjv192. View

11.

Lombard M, Steyn N, Charlton K, Senekal M . Application and interpretation of multiple statistical tests to evaluate validity of dietary intake assessment methods. Nutr J. 2015; 14:40. PMC: 4471918. DOI: 10.1186/s12937-015-0027-y. View

12.

Lomer M . Dietary and nutritional considerations for inflammatory bowel disease. Proc Nutr Soc. 2011; 70(3):329-35. DOI: 10.1017/S0029665111000097. View

13.

Cade J, Burley V, Warm D, Thompson R, Margetts B . Food-frequency questionnaires: a review of their design, validation and utilisation. Nutr Res Rev. 2008; 17(1):5-22. DOI: 10.1079/NRR200370. View

14.

Peters V, Tigchelaar-Feenstra E, Imhann F, Dekens J, Swertz M, Franke L . Habitual dietary intake of IBD patients differs from population controls: a case-control study. Eur J Nutr. 2020; 60(1):345-356. PMC: 7867519. DOI: 10.1007/s00394-020-02250-z. View

15.

van Dongen M, Wijckmans-Duysens N, den Biggelaar L, Ocke M, Meijboom S, Brants H . The Maastricht FFQ: Development and validation of a comprehensive food frequency questionnaire for the Maastricht study. Nutrition. 2019; 62:39-46. DOI: 10.1016/j.nut.2018.10.015. View

16.

Bland J, Altman D . Measuring agreement in method comparison studies. Stat Methods Med Res. 1999; 8(2):135-60. DOI: 10.1177/096228029900800204. View

17.

Ananthakrishnan A, Bernstein C, Iliopoulos D, MacPherson A, Neurath M, Raja Ali R . Environmental triggers in IBD: a review of progress and evidence. Nat Rev Gastroenterol Hepatol. 2017; 15(1):39-49. DOI: 10.1038/nrgastro.2017.136. View

18.

Steinemann N, Grize L, Ziesemer K, Kauf P, Probst-Hensch N, Brombach C . Relative validation of a food frequency questionnaire to estimate food intake in an adult population. Food Nutr Res. 2017; 61(1):1305193. PMC: 5404419. DOI: 10.1080/16546628.2017.1305193. View

19.

Imhann F, Van der Velde K, Barbieri R, Alberts R, Voskuil M, Vich Vila A . The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1. BMC Gastroenterol. 2019; 19(1):5. PMC: 6325838. DOI: 10.1186/s12876-018-0917-5. View

20.

Peters V, Alizadeh B, de Vries J, Dijkstra G, Campmans-Kuijpers M . Nutritional Assessment in Inflammatory Bowel Disease (IBD)-Development of the Groningen IBD Nutritional Questionnaires (GINQ). Nutrients. 2019; 11(11). PMC: 6893781. DOI: 10.3390/nu11112739. View