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Histological Research and Phytochemical Characterization of Medik. from Bihor County, Romania

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Journal Life (Basel)
Date 2025 Jan 25
PMID 39860007
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Abstract

Medik. (CBP) is a species with antibacterial, anti-inflammatory, antioxidant, anticancer, and hepatoprotective effects. We have chosen to study this species because, although it is a common plant with a distinctive fruit appearance, its effects are not fully understood. The aim of this study was to characterize the histoanatomy of the vegetative, reproductive organs and to characterize CBP extracts in terms of bioactive compounds and its antioxidant capacity. This study investigated the quantitative chemical composition of this species using the HPLC method, revealing the total content in polyphenols, flavonoids, and anthocyanins, and investigated the antioxidant potential through fluorescence recovery after photobleaching (FRAP assay), cupric ion (Cu) reduction, (CUPRAC assay), and a free radical scavenging method (DPPH). Our results show that CBP is a rich source of flavonoids, mainly from the extract obtained from the fruits; it has an antioxidant capacity, with the highest values being obtained from mature flowers and ripe fruits. Of the active principles, the highest amounts, according to HPLC determinations, were obtained in flowers and are represented by hyperoside. Thus, we can recommend the studied species for phytopharmaceutical preparations.

References
1.
Tulipani S, Mezzetti B, Capocasa F, Bompadre S, Beekwilder J, de Vos C . Antioxidants, phenolic compounds, and nutritional quality of different strawberry genotypes. J Agric Food Chem. 2008; 56(3):696-704. DOI: 10.1021/jf0719959. View

2.
Kaplanski G, Marin V, Montero-Julian F, Mantovani A, Farnarier C . IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation. Trends Immunol. 2002; 24(1):25-9. DOI: 10.1016/s1471-4906(02)00013-3. View

3.
Li Y, Zhang T, Korkaya H, Liu S, Lee H, Newman B . Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin Cancer Res. 2010; 16(9):2580-90. PMC: 2862133. DOI: 10.1158/1078-0432.CCR-09-2937. View

4.
Trifan D, Tirla A, Moldovan A, Mos C, Bodog F, Maghiar T . Can Vitamin D Levels Alter the Effectiveness of Short-Term Facelift Interventions?. Healthcare (Basel). 2023; 11(10). PMC: 10218689. DOI: 10.3390/healthcare11101490. View

5.
Ghalandari S, Kariman N, Sheikhan Z, Mojab F, Mirzaei M, Shahrahmani H . Effect of Hydroalcoholic Extract of Capsella bursa pastoris on Early Postpartum Hemorrhage: A Clinical Trial Study. J Altern Complement Med. 2017; 23(10):794-799. DOI: 10.1089/acm.2017.0095. View