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Artificial Intelligence in Pediatric Epilepsy Detection: Balancing Effectiveness With Ethical Considerations for Welfare

Overview
Journal Health Sci Rep
Date 2025 Jan 23
PMID 39846037
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Abstract

Background And Aim: Epilepsy is a major neurological challenge, especially for pediatric populations. It profoundly impacts both developmental progress and quality of life in affected children. With the advent of artificial intelligence (AI), there's a growing interest in leveraging its capabilities to improve the diagnosis and management of pediatric epilepsy. This review aims to assess the effectiveness of AI in pediatric epilepsy detection while considering the ethical implications surrounding its implementation.

Methodology: A comprehensive systematic review was conducted across multiple databases including PubMed, EMBASE, Google Scholar, Scopus, and Medline. Search terms encompassed "pediatric epilepsy," "artificial intelligence," "machine learning," "ethical considerations," and "data security." Publications from the past decade were scrutinized for methodological rigor, with a focus on studies evaluating AI's efficacy in pediatric epilepsy detection and management.

Results: AI systems have demonstrated strong potential in diagnosing and monitoring pediatric epilepsy, often matching clinical accuracy. For example, AI-driven decision support achieved 93.4% accuracy in diagnosis, closely aligning with expert assessments. Specific methods, like EEG-based AI for detecting interictal discharges, showed high specificity (93.33%-96.67%) and sensitivity (76.67%-93.33%), while neuroimaging approaches using rs-fMRI and DTI reached up to 97.5% accuracy in identifying microstructural abnormalities. Deep learning models, such as CNN-LSTM, have also enhanced seizure detection from video by capturing subtle movement and expression cues. Non-EEG sensor-based methods effectively identified nocturnal seizures, offering promising support for pediatric care. However, ethical considerations around privacy, data security, and model bias remain crucial for responsible AI integration.

Conclusion: While AI holds immense potential to enhance pediatric epilepsy management, ethical considerations surrounding transparency, fairness, and data security must be rigorously addressed. Collaborative efforts among stakeholders are imperative to navigate these ethical challenges effectively, ensuring responsible AI integration and optimizing patient outcomes in pediatric epilepsy care.

References
1.
Armand Larsen S, Terney D, Osterkjerhuus T, Vinding Merinder T, Annala K, Knight A . Automated detection of nocturnal motor seizures using an audio-video system. Brain Behav. 2022; 12(9):e2737. PMC: 9480955. DOI: 10.1002/brb3.2737. View

2.
Maher C, Yang Y, Truong N, Wang C, Nikpour A, Kavehei O . Seizure detection with reduced electroencephalogram channels: research trends and outlook. R Soc Open Sci. 2023; 10(5):230022. PMC: 10154941. DOI: 10.1098/rsos.230022. View

3.
Natu M, Bachute M, Gite S, Kotecha K, Vidyarthi A . Review on Epileptic Seizure Prediction: Machine Learning and Deep Learning Approaches. Comput Math Methods Med. 2022; 2022:7751263. PMC: 8794701. DOI: 10.1155/2022/7751263. View

4.
Kelly C, Karthikesalingam A, Suleyman M, Corrado G, King D . Key challenges for delivering clinical impact with artificial intelligence. BMC Med. 2019; 17(1):195. PMC: 6821018. DOI: 10.1186/s12916-019-1426-2. View

5.
Modi A, Guilfoyle S, Mann K, Rausch J . A pilot randomized controlled clinical trial to improve antiepileptic drug adherence in young children with epilepsy. Epilepsia. 2015; 57(3):e69-75. PMC: 4783218. DOI: 10.1111/epi.13289. View