Predicting Extubation Failure in Neonates: The Role of Lung Ultrasound and Corrected Gestational Age in Safe Weaning in the NICU

Overview

Journal Eur J Pediatr

Date 2025 Jan 17

PMID 39825155

Authors

Bruna Schafer Rojas

Renato Soibelmann Procianoy

Ana Carolina Menezes de Souza

Cristiane Cover Rigodanzo

Gabriela S Trindade

Silvana Piazza Furlan

Rita C Silveira

Affiliations

Soon will be listed here.

Abstract

Conclusion: LUS show promise in predicting weaning failure, though its accuracy may be limited in extremely preterm infants, highlighting the need for further well-powered studies. CGA at extubation also emerges as a key consideration in this population, warranting confirmation through robust future research.

What Is Known: • Identifying the optimal timing for extubation is crucial, as both prolonged mechanical ventilation and failed extubation are linked to increased morbidity. • Lung ultrasound plays a well-established role in diagnosing various neonatal lung pathologies, allowing clinicians to make rapid, bedside decisions for the treatment of newborns.

What Is New: • LUS appears to be accurate in predicting weaning failure, though its accuracy may be lower in extremely preterm infants. • In extremely preterm infants, CGA may play an important role in extubation decision-making. • These findings are hypothesis-generating and warrant further investigation in future studies.

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