Artificial Womb Technology - A More Physiologic Solution to Treating Extreme Prematurity

Overview

Journal Eur J Obstet Gynecol Reprod Biol X

Date 2025 Jan 16

PMID 39817031

Authors

Felix R De Bie

Chase C Binion

Ryan M Antiel

Affiliations

Soon will be listed here.

Abstract

Treatment of extreme premature infants (EPI) is limited by developmental immaturity primarily of the lung. A paradigm shift towards a more physiologic treatment of EPI as fetal neonates or , by keeping them in a womb-like environment to allow continued organ maturation, is the rationale for artificial womb technology. In this review, we discuss the artificial placenta and womb technology, it's rationale, the history of its development, the most recent preclinical models described in the literature and finally pertinent ethical considerations.

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