Yoga Practice As a Potential Sarcopenia Prevention Strategy in Indonesian Older Adults: A Cross-Sectional Study

Overview

Journal Open Access J Sports Med

Publisher Dove Medical Press

Date 2025 Jan 16

PMID 39816476

Authors

Anna Meiliana

Nurrani Mustika Dewi

Irma Rahayu Latarissa

Melisa Intan Barliana

Sofa Dewi Alfian

Trilis Yulianti

Andi Wijaya

Affiliations

Soon will be listed here.

Abstract

Background: Sarcopenia is characterized by the progressive loss of skeletal muscle mass and poses a significant health challenge for older adults by increasing the risk of disability and decreasing quality of life. Yoga considers as a low-risk and beneficial exercise for older adults. This research aims to evaluate the potential of yoga practice as a preventive strategy against sarcopenia in Indonesian older adults.

Methods: An observational cross-sectional research was conducted including 41 older adults aged 60-87 years. The research focused on key biomarkers and functional assessments, including serum insulin-like growth factor 1 (IGF-1) levels, telomere length, gait speed, hand grip strength, and SARC-F questionnaire scores.

Results: The results showed that participants aged 71-80 years who practiced yoga for more than a year had significantly higher IGF-1 levels (p=0.04). While improvements in gait speed, hand grip strength, and SARC-F scores were observed, these changes were not statistically significant, and no significant differences were found in telomere length.

Conclusion: Yoga in older adults was associated with higher IGF-1 levels and potential improvements in upper and lower extremity strength, though these findings were not statistically significant and did not influence telomere length. Yoga practice shows potential as an emerging adjuvant option but can not be applied as a single strategy for sarcopenia prevention in older adults.

References

Aroogh M, Mohammadi Shahboulaghi F . Social Participation of Older Adults: A Concept Analysis. Int J Community Based Nurs Midwifery. 2020; 8(1):55-72. PMC: 6969951. DOI: 10.30476/IJCBNM.2019.82222.1055. View

OCallaghan N, Fenech M . A quantitative PCR method for measuring absolute telomere length. Biol Proced Online. 2011; 13:3. PMC: 3047434. DOI: 10.1186/1480-9222-13-3. View

Xiang Y, Zhang M, Jiang D, Su Q, Shi J . The role of inflammation in autoimmune disease: a therapeutic target. Front Immunol. 2023; 14:1267091. PMC: 10584158. DOI: 10.3389/fimmu.2023.1267091. View

Zhao Y, Liao L, Feng H, Chen H, Ning H . Correction to: Enablers and barriers to implementing care quality improvement program in nursing homes in China. BMC Geriatr. 2022; 22(1):1. PMC: 8722059. DOI: 10.1186/s12877-021-02658-0. View

Papalia G, Papalia R, Diaz Balzani L, Torre G, Zampogna B, Vasta S . The Effects of Physical Exercise on Balance and Prevention of Falls in Older People: A Systematic Review and Meta-Analysis. J Clin Med. 2020; 9(8). PMC: 7466089. DOI: 10.3390/jcm9082595. View

Gui R, Li W, Li Z, Wang H, Wu Y, Jiao W . Effects and potential mechanisms of IGF1/IGF1R in the liver fibrosis: A review. Int J Biol Macromol. 2023; 251:126263. DOI: 10.1016/j.ijbiomac.2023.126263. View

Malmstrom T, Morley J . SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. J Am Med Dir Assoc. 2013; 14(8):531-2. DOI: 10.1016/j.jamda.2013.05.018. View

Beaudart C, McCloskey E, Bruyere O, Cesari M, Rolland Y, Rizzoli R . Sarcopenia in daily practice: assessment and management. BMC Geriatr. 2016; 16(1):170. PMC: 5052976. DOI: 10.1186/s12877-016-0349-4. View

Zeng L, Xu Q . eNOS-ERalpha complex goes to telomerase. Circ Res. 2008; 103(1):10-2. DOI: 10.1161/CIRCRESAHA.108.179986. View

Verdijk L, Snijders T, Drost M, Delhaas T, Kadi F, van Loon L . Satellite cells in human skeletal muscle; from birth to old age. Age (Dordr). 2013; 36(2):545-7. PMC: 4039250. DOI: 10.1007/s11357-013-9583-2. View

10.

Ludlow A, Roth S . Physical activity and telomere biology: exploring the link with aging-related disease prevention. J Aging Res. 2011; 2011:790378. PMC: 3043290. DOI: 10.4061/2011/790378. View

11.

Chen L, Woo J, Assantachai P, Auyeung T, Chou M, Iijima K . Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc. 2020; 21(3):300-307.e2. DOI: 10.1016/j.jamda.2019.12.012. View

12.

Bardon L, Corish C, Lane M, Bizzaro M, Loayza Villarroel K, Clarke M . Ageing rate of older adults affects the factors associated with, and the determinants of malnutrition in the community: a systematic review and narrative synthesis. BMC Geriatr. 2021; 21(1):676. PMC: 8642873. DOI: 10.1186/s12877-021-02583-2. View

13.

Nishiguchi S, Yamada M, Fukutani N, Adachi D, Tashiro Y, Hotta T . Differential association of frailty with cognitive decline and sarcopenia in community-dwelling older adults. J Am Med Dir Assoc. 2014; 16(2):120-4. DOI: 10.1016/j.jamda.2014.07.010. View

14.

Hernandez-Alvarez D, Rosado-Perez J, Gavia-Garcia G, Arista-Ugalde T, Aguiniga-Sanchez I, Santiago-Osorio E . Aging, Physical Exercise, Telomeres, and Sarcopenia: A Narrative Review. Biomedicines. 2023; 11(2). PMC: 9952920. DOI: 10.3390/biomedicines11020598. View

15.

Lamers S, Kasim Z, Rodriguez-Garcia W, Kalmet P, Perkisas S, De Cock A . Validation of SARC-F-Proxy for the Screening of Sarcopenia in Older Patients with Cognitive Impairment. J Frailty Sarcopenia Falls. 2023; 8(4):204-210. PMC: 10690132. DOI: 10.22540/JFSF-08-204. View

16.

Hepple R . Mitochondrial involvement and impact in aging skeletal muscle. Front Aging Neurosci. 2014; 6:211. PMC: 4159998. DOI: 10.3389/fnagi.2014.00211. View

17.

Krejci M, Hill M, Kajzar J, Tichy M, Hosek V . Yoga Exercise Intervention Improves Balance Control and Prevents Falls in Seniors Aged 65. Zdr Varst. 2022; 61(2):85-92. PMC: 8937584. DOI: 10.2478/sjph-2022-0012. View

17.

Rakita A, Nikolic N, Mildner M, Matiasek J, Elbe-Burger A . Re-epithelialization and immune cell behaviour in an ex vivo human skin model. Sci Rep. 2020; 10(1):1. PMC: 6959339. DOI: 10.1038/s41598-019-56847-4. View

18.

Cawthon R . Telomere measurement by quantitative PCR. Nucleic Acids Res. 2002; 30(10):e47. PMC: 115301. DOI: 10.1093/nar/30.10.e47. View