Handgrip and Its Relation to Age, Fragility Fractures, and BMD Between Sexes in a Population Aged 50+ Years

Overview

Journal Prz Menopauzalny

Publisher Termedia

Date 2025 Jan 15

PMID 39811384

Authors

Jaroslaw Amarowicz

Maja Warzecha

Agnieszka Krawczyk

Affiliations

Soon will be listed here.

Abstract

Introduction: A decrease in bone mineral density (BMD) accompanied by muscle weakness during aging significantly increases the probability of low-energy fracture occurrence, but it can also happen in those with a non-osteoporotic score (treatment gap). To improve the identification process of those at risk, the authors proposed using the interconnectivity between bone mineral density and muscle tissue.

Material And Methods: A total of 20,776 patient records were collected from the database in the period 2008-2021. After applying inclusion criteria, a total of 7159 records were used in the study. Questionnaires regarding patients' history were collected at admission. Patients underwent lumbar spine and/or femoral neck DXA examination and handgrip testing with a handheld dynamometer. Statistical analysis was conducted using tests suitable for the distribution of the data.

Results: Osteoporosis was diagnosed in a total of 1914 patients. Depending on the diagnosis there was a significant ( < 0.001) difference in handgrip strength (HGS) between the BMD statuses (norm-osteopenia-osteoporosis). HGS was significantly ( < 0.001) correlated with both BMD neck ( = 0.2) and spine ( = 0.1) in females, and with BMD neck ( = 0.11) in the male population. In our study group HGS was significantly ( < 0.001) higher for all the analysed fractures in the no-fracture group of women. There was no such relationship in reference to the male population.

Conclusions: Due to its relationship with BMD, its low cost, and availability, HGS might prove useful in identifying women at risk of a fragility fracture.

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