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Refractory and Relapsing Laryngeal Edema Possibly Associated With Chronic Tonsillitis and Mycoplasma Infection, Requiring Reintubation and Tracheostomy

Overview
Journal Case Rep Med
Publisher Wiley
Date 2025 Jan 13
PMID 39801600
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Abstract

Relapsing epiglottitis has rarely been reported, and its etiology is not well established. A 44-year-old previously healthy Japanese man presented with a quickly progressing choking sensation. He had been experiencing refractory and relapsing laryngeal edema and probably acute epiglottitis (three episodes within 2 weeks), with rash and elevated pancreatic amylase. The patient required immediate intubation. After the initial extubation, he required reintubation and a subsequent tracheostomy. Antibiotics, glucocorticoid, and antihistamines were administered, and he finally recovered with the tracheostomy's closure. Potential causes of this patient's relapsing epiglottitis are as follows: persistent right swollen tonsil; a positive result on a Mycoplasma pneumoniae antigen test and a particle agglutination (PA) test, implicating chronic tonsillitis; and/or Mycoplasma infection. This is the first case report of refractory and relapsing epiglottitis requiring reintubation possibly concurrent with chronic tonsillitis and Mycoplasma infection.

References
1.
Yoon S, Min I, Ahn J . Immunochromatography for the diagnosis of Mycoplasma pneumoniae infection: A systematic review and meta-analysis. PLoS One. 2020; 15(3):e0230338. PMC: 7077834. DOI: 10.1371/journal.pone.0230338. View

2.
Narita M . Classification of Extrapulmonary Manifestations Due to Mycoplasma pneumoniae Infection on the Basis of Possible Pathogenesis. Front Microbiol. 2016; 7:23. PMC: 4729911. DOI: 10.3389/fmicb.2016.00023. View

3.
Ye Q, Mao J, Shu Q, Shang S . Mycoplasma pneumoniae induces allergy by producing P1-specific immunoglobulin E. Ann Allergy Asthma Immunol. 2018; 121(1):90-97. DOI: 10.1016/j.anai.2018.03.014. View

4.
Chroboczek T, Cour M, Hernu R, Baudry T, Bohe J, Piriou V . Long-term outcome of critically ill adult patients with acute epiglottitis. PLoS One. 2015; 10(5):e0125736. PMC: 4422676. DOI: 10.1371/journal.pone.0125736. View

5.
Guss D, Jackson J . Recurring epiglottitis in an adult. Ann Emerg Med. 1987; 16(4):441-4. DOI: 10.1016/s0196-0644(87)80368-2. View