» Articles » PMID: 39786603

Environmental Factors Inducing Gastric Cancer: Insights into Risk and Prevention Strategies

Overview
Journal Discov Oncol
Publisher Springer
Date 2025 Jan 9
PMID 39786603
Authors
Affiliations
Soon will be listed here.
Abstract

Gastric cancer, a prevalent malignant tumor worldwide, poses a significant challenge to global health. Despite ongoing advancements in treatment methods, its high incidence and mortality rates remain concerning. Although progress in treating gastric cancer is encouraging, a more critical focus is on enhancing prevention efforts. Understanding the risk factors associated with gastric cancer is crucial for its prevention. This article summarizes the environmental factors related to the development of gastric cancer and their prevention, including: Living or working environment factors (air pollution, water quality, soil pollution, radiation, altitude, climate), dietary habits (meat, high-fat diet, high-salt diet), lifestyle habits (smoking, Drinking, sleep, coffee), and viral and bacterial exposures (Epstein-Barr virus, Human cytomegalovirus, Helicobacter pylori). Additionally, the article discusses current research directions and aims to provide a reference for researchers, paving the way for future preventive and therapeutic strategies.

References
1.
Kijima Y, Ishigami S, Hokita S, Koriyama C, Akiba S, Eizuru Y . The comparison of the prognosis between Epstein-Barr virus (EBV)-positive gastric carcinomas and EBV-negative ones. Cancer Lett. 2003; 200(1):33-40. DOI: 10.1016/s0304-3835(03)00410-5. View

2.
Ge S, Feng X, Shen L, Wei Z, Zhu Q, Sun J . Association between Habitual Dietary Salt Intake and Risk of Gastric Cancer: A Systematic Review of Observational Studies. Gastroenterol Res Pract. 2012; 2012:808120. PMC: 3485508. DOI: 10.1155/2012/808120. View

3.
Anghileri L . Magnesium, calcium and cancer. Magnes Res. 2010; 22(4):247-55. DOI: 10.1684/mrh.2009.0173. View

4.
Zeng S, Weng H, Zhou M, Duan X, Shen X, Zeng X . Long-Term Coffee Consumption and Risk of Gastric Cancer: A PRISMA-Compliant Dose-Response Meta-Analysis of Prospective Cohort Studies. Medicine (Baltimore). 2015; 94(38):e1640. PMC: 4635778. DOI: 10.1097/MD.0000000000001640. View

5.
Li L, Gan Y, Wu C, Qu X, Sun G, Lu Z . Coffee consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies. BMC Cancer. 2015; 15:733. PMC: 4615385. DOI: 10.1186/s12885-015-1758-z. View