Prevalence and Quality of Life Associated with Erectile Dysfunction and Lower Urinary Tract Symptoms: a Cross-sectional Study

Overview

Journal Sao Paulo Med J

Specialty General Medicine

Date 2025 Jan 8

PMID 39774734

Authors

Felipe Jun Kijima

Liz Cristina Motta

Jean Sousa Cavalcante

Lucas Jordao

Carlos Eduardo Dias Olioze

Plinio Takashi Karubi Palavicini Santos

Joao Carlos Leite da Cruz

Luis Expedito Sabage

Gabriel Araujo Medeiros

Alessandra Mazzo

Aguinaldo Cesar Nardi

Affiliations

Soon will be listed here.

Abstract

Background: Genitourinary health significantly affects the quality of life of men, particularly those in middle age. Recent studies have shown that more than half of the men aged over 40 years experience some degree of low urinary tract symptoms (LUTS) or erectile dysfunction (ED).

Objective: To assess the prevalence of ED and LUTS in middle-aged men and correlate this with quality of life data.

Design And Setting: A cross-sectional study was conducted in a municipality in the countryside of São Paulo.

Methods: A trained team collected data between July 2021 and August 2022 through face-to-face interviews using a characterization instrument, International Prostate Symptom Score (IPSS), International Index of Erectile Function-6 (IIEF-6), and World Health Organization Quality-of-Life Scale.

Results: The study included 375 male participants with a median age of 53 years (interquartile range [IQR] 38.5-66). The IIEF-6 showed the presence of some degree of ED in 51.1% (n = 188) of patients, with a median score of 25 (IQR 21-29). The IPSS revealed that 35.2% (n = 132) of the patients had some degree of LUTS, with a median score of 5 (IQR 2-11). The urological questionnaires had a direct proportional correlation with age (P < 0.001) and significant differences between the medians of different marital statuses (P < 0.001). The presence or severity of these disorders was inversely correlated with the individuals' quality of life (P < 0.001).

Conclusions: ED and LUTS significantly correlated with the quality of life, marital status, and age in men.

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