Diphtheria Toxin-Producing Corynebacterium Ramonii in Inner-City Population, Vancouver, British Columbia, Canada, 2019-2023
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
We conducted patient chart reviews and whole-genome sequencing of wound specimens containing presumptive Corynebacterium ulcerans from Vancouver, British Columbia, Canada, during July 2019-July 2023. Sequencing confirmed 8/14 isolates were C. ramonii and identified 2 distinct clusters. Molecular methods should be used to clinically differentiate potential toxin-producing Corynebacterium spp.
References
1.
Zhou Z, Alikhan N, Sergeant M, Luhmann N, Vaz C, Francisco A
. GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens. Genome Res. 2018; 28(9):1395-1404.
PMC: 6120633.
DOI: 10.1101/gr.232397.117.
View
2.
Kolmogorov M, Yuan J, Lin Y, Pevzner P
. Assembly of long, error-prone reads using repeat graphs. Nat Biotechnol. 2019; 37(5):540-546.
DOI: 10.1038/s41587-019-0072-8.
View
3.
Chorlton S, Ritchie G, Lawson T, Romney M, Lowe C
. Whole-Genome Sequencing of Corynebacterium diphtheriae Isolates Recovered from an Inner-City Population Demonstrates the Predominance of a Single Molecular Strain. J Clin Microbiol. 2019; 58(2).
PMC: 6989084.
DOI: 10.1128/JCM.01651-19.
View
4.
Tonkin-Hill G, MacAlasdair N, Ruis C, Weimann A, Horesh G, Lees J
. Producing polished prokaryotic pangenomes with the Panaroo pipeline. Genome Biol. 2020; 21(1):180.
PMC: 7376924.
DOI: 10.1186/s13059-020-02090-4.
View
5.
Argimon S, Abudahab K, Goater R, Fedosejev A, Bhai J, Glasner C
. Microreact: visualizing and sharing data for genomic epidemiology and phylogeography. Microb Genom. 2017; 2(11):e000093.
PMC: 5320705.
DOI: 10.1099/mgen.0.000093.
View